ArticleJournal of clinical microbiology1994
Genetic diversity in human-derived Pneumocystis carinii isolates from four geographical locations shown by analysis of mitochondrial rRNA gene sequences.
Article in Journal of clinical microbiology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 78 citations in OpenAlex.
- Combined use of blood and oropharyngeal samples for noninvasive diagnosis of Pneumocystis carinii pneumonia using the polymerase chain reaction.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 1998Trial
- A Molecular Window into the Biology and Epidemiology of Pneumocystis spp.Clinical microbiology reviews · 2018Review
- Multilocus microsatellite genotyping array for investigation of genetic epidemiology of Pneumocystis jirovecii.Journal of clinical microbiology · 2014Article
- Prevalence and genotype distribution of Pneumocystis jirovecii in Cuban infants and toddlers with whooping cough.Journal of clinical microbiology · 2014Article
- Genetic diversity of Pneumocystis carinii f. sp. hominis based on variations in nucleotide sequences of internal transcribed spacers of rRNA genes.Journal of clinical microbiology · 2002Article
- Heterogeneity and compartmentalization of Pneumocystis carinii f. sp. hominis genotypes in autopsy lungs.Journal of clinical microbiology · 2001Article
- Genetic diversity of Pneumocystis carinii isolated from human immunodeficiency virus-positive patients in Turin, Italy.Journal of clinical microbiology · 2001Article
- Internal transcribed spacer regions of rRNA genes of Pneumocystis carinii from monkeys.Clinical and diagnostic laboratory immunology · 2001Article
- Variation of antigenicity and serological reaction to Pneumocystis carinii in Korea.The Korean journal of parasitology · 1999Article
- Identification of Pneumocystis carinii f. sp. hominis gene sequences in filtered air in hospital environments.Journal of clinical microbiology · 1998Article
- Update on Pneumocystis carinii f. sp. hominis typing based on nucleotide sequence variations in internal transcribed spacer regions of rRNA genes.Journal of clinical microbiology · 1998Article
- Pre-AIDS era isolates of Pneumocystis carinii f. sp. hominis: high genotype similarity with contemporary isolates.Journal of clinical microbiology · 1998Article
- Typing of Pneumocystis carinii f. sp. hominis by single-strand conformation polymorphism of four genomic regions.Journal of clinical microbiology · 1997Article
- Simplified sample processing combined with a sensitive one-tube nested PCR assay for detection of Pneumocystis carinii in respiratory specimens.Journal of clinical microbiology · 1997Article
- Study of internal transcribed spacer and mitochondrial large-subunit genes of Pneumocystis carinii hominis isolated by repeated bronchoalveolar lavage from human immunodeficiency virus-infected patients during one or several episodes of pneumonia.Journal of clinical microbiology · 1997Article
- Biodiversity of Pneumocystis carinii hominis: typing with different DNA regions.Journal of clinical microbiology · 1997Article
- Development of type-specific PCR for typing Pneumocystis carinii f. sp. hominis based on nucleotide sequence variations of internal transcribed spacer region of rRNA genes.Journal of clinical microbiology · 1996Article
- Pneumocystis carinii: what is it, exactly?Clinical microbiology reviews · 1996Review
- DNA sequences identical to Pneumocystis carinii f. sp. carinii and Pneumocystis carinii f. sp. hominis in samples of air spora.Journal of clinical microbiology · 1996Article
- Diversity of host species and strains of Pneumocystis carinii is based on rRNA sequences.Clinical and diagnostic laboratory immunology · 1996Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The opportunistic fungal pathogen Pneumocystis carinii is a frequent cause of pneumonia in immunocompromised hosts. In this study, we have compared the DNA sequences of a portion of the mitochondrial large-subunit rRNA gene of P. carinii (an informative locus showing up to 27% differences among isolates of P. carinii from human-, rat-, mouse-, ferret-, rabbit-, and horse-infected lungs) obtained from human-derived isolates from widely disparate geographical areas, including Britain, the United States, Brazil, and Zimbabwe. A single-base polymorphism which varied among samples was identified. Apart from this nucleotide, the DNA sequences of all samples were identical. The sequences of the British samples were shown to be stable over a period of 4 years. These data suggest that there is relatively low genetic diversity among isolates of human-derived P. carinii from different global regions.
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