ReviewPharmacology & therapeutics1994
Picornavirus inhibitors.
Review in Pharmacology & therapeutics, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Complete sequence analysis and antiviral screening of medicinal plants for human coxsackievirus a16 isolated in Korea.Osong public health and research perspectives · 2015Article
- In vitro and in vivo studies of the inhibitory effects of emodin isolated from Polygonum cuspidatum on Coxsakievirus B₄.Molecules (Basel, Switzerland) · 2013Article
- Enterovirus infection in Korean children and anti-enteroviral potential candidate agents.Korean journal of pediatrics · 2012Article
- Antiviral activity of Arbidol against Coxsackie virus B5 in vitro and in vivo.Archives of virology · 2009Article
- Rhinovirus chemotherapy.Antiviral research · 2006Review
- In vitro screening of traditionally used medicinal plants in China against enteroviruses.World journal of gastroenterology · 2006Article
- Inhibition of polyprotein processing and RNA replication of human rhinovirus by pyrrolidine dithiocarbamate involves metal ions.Journal of virology · 2005Article
- Entry is a rate-limiting step for viral infection in a Drosophila melanogaster model of pathogenesis.Nature immunology · 2004Article
- Antiviral effects of pyrrolidine dithiocarbamate on human rhinoviruses.Journal of virology · 2002Article
- Efficient virus extinction by combinations of a mutagen and antiviral inhibitors.Journal of virology · 2001Article
- In vitro antiviral activity of AG7088, a potent inhibitor of human rhinovirus 3C protease.Antimicrobial agents and chemotherapy · 1999Article
- Cleavage of eukaryotic translation initiation factor 4G by exogenously added hybrid proteins containing poliovirus 2Apro in HeLa cells: effects on gene expression.Molecular and cellular biology · 1999Article
- Protease inhibitors as antiviral agents.Clinical microbiology reviews · 1998Review
- Foot-and-mouth disease virus and poliovirus particles contain proteins of the replication complex.Journal of virology · 1997Article
- Poliovirus infection and expression of the poliovirus protein 2B provoke the disassembly of the Golgi complex, the organelle target for the antipoliovirus drug Ro-090179.Journal of virology · 1997Article
- Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- Viral cysteine proteinases.Perspectives in drug discovery and design : PD3 · 1996Article
- Simple in vitro translation assay to analyze inhibitors of rhinovirus proteases.Antimicrobial agents and chemotherapy · 1996Article
- A poliovirus 2A(pro) mutant unable to cleave 3CD shows inefficient viral protein synthesis and transactivation defects.Journal of virology · 1995Article
- Enhanced intracellular calcium concentration during poliovirus infection.Journal of virology · 1995Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Picornaviruses are among the best understood animal viruses in molecular terms. A number of important human and animal pathogens are members of the Picornaviridae family. The genome organization, the different steps of picornavirus growth and numerous compounds that have been reported as inhibitors of picornavirus functions are reviewed. The picornavirus particles and several agents that interact with them have been solved at atomic resolution, leading to computer-assisted drug design. Picornavirus inhibitors are useful in aiding a better understanding of picornavirus biology. In addition, some of them are promising therapeutic agents. Clinical efficacy of agents that bind to picornavirus particles has already been demonstrated.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.