Evidence map›Paper›PMID 7531280›Full record

ReviewMolecular biology reports1994

Perspectives on zinc finger protein function and evolution--an update.

T Pieler, E Bellefroid

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 102 citations in OpenAlex.

  1. Article
  2. Zinc and gastrointestinal disease.World journal of gastrointestinal pathophysiology · 2014
    Review
  3. Article
  4. Article
  5. Heritable endogenous gene regulation in plants with designed polydactyl zinc finger transcription factors.Proceedings of the National Academy of Sciences of the United States of America · 2002
    Article
  6. Article
  7. Article
  8. Positional cloning of ZNF217 and NABC1: genes amplified at 20q13.2 and overexpressed in breast carcinoma.Proceedings of the National Academy of Sciences of the United States of America · 1998
    Article
  9. Antigenic variation in Giardia lamblia and the host's immune response.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 1997
    Review
  10. Exploring the role of homeobox and zinc finger proteins in pancreatic cell proliferation, differentiation, and apoptosis.International journal of pancreatology : official journal of the International Association of Pancreatology · 1997
    Review
  11. Article
  12. Molecular cloning and mapping of a novel developmentally regulated human C2H2-type zinc finger.Mammalian genome : official journal of the International Mammalian Genome Society · 1997
    Article
  13. Article
  14. Chromosomal location of fifteen unique mouse KRAB-containing zinc finger loci.Mammalian genome : official journal of the International Mammalian Genome Society · 1996
    Article
  15. Article
  16. Article
  17. Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.Proceedings of the National Academy of Sciences of the United States of America · 1995
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

T PielerInstitut für Biochemie und Molekulare Zellbiologie, Göttingen, Germany.
E Bellefroid
Institut für Wildbiologie Göttingen und Dresden · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Complexity is one of the hallmarks that applies to C2H2 type zinc finger proteins (ZFPs). Structurally distinct clusters of zinc finger modules define an extremely large superfamily of nucleic acid binding proteins with several hundred, perhaps thousands of different members in vertebrates. Recent discoveries have provided new insights into the biochemistry of RNA and DNA recognition, into ZFP evolution and genomic organization, and also into basic aspects of their biological function. However, as much as we have learned, other fundamental questions about ZFP function remain highly enigmatic. This essay is meant to define what we personally feel are important questions, rather than trying to provide a comprehensive, encyclopaedic review.

Indexed as

Biological EvolutionAmino Acid SequenceAnimalsDNADNA-Binding ProteinsEmbryonic and Fetal DevelopmentMolecular Sequence DataRNAVertebratesZinc FingersDNADNA-Binding ProteinsRNA

Identifiers

PMID7531280
OpenAlexW2036670909

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.