ArticleProtein science : a publication of the Protein Society1994
Extending the B7 (CD80) gene family.
Article in Protein science : a publication of the Protein Society, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
24 citing papers in PubMed.
- BTN2A2 protein negatively regulates T cells to ameliorate collagen-induced arthritis in mice.Scientific reports · 2021Article
- ERMAP is a B7 family-related molecule that negatively regulates T cell and macrophage responses.Cellular & molecular immunology · 2021Article
- Skint8, a Novel B7 Family-Related Molecule, Negatively Regulates T Cell Responses.Journal of immunology (Baltimore, Md. : 1950) · 2019Article
- BTNL2-Ig Protein Attenuates Type 1 Diabetes in Non-Obese Diabetic (NOD) Mice.Advanced healthcare materials · 2019Article
- In vivo administration of recombinant BTNL2-Fc fusion protein ameliorates graft-versus-host disease in mice.Cellular immunology · 2019Article
- Evolutionary and polymorphism analyses reveal the central role of BTN3A2 in the concerted evolution of the BTN3 gene family.Immunogenetics · 2017Article
- A common 56-kilobase deletion in a primate-specific segmental duplication creates a novel butyrophilin-like protein.BMC genetics · 2013Article
- The butyrophilin (BTN) gene family: from milk fat to the regulation of the immune response.Immunogenetics · 2012Review
- Evolution of the B7 family: co-evolution of B7H6 and NKp30, identification of a new B7 family member, B7H7, and of B7's historical relationship with the MHC.Immunogenetics · 2012Article
- BTN3A2 expression in epithelial ovarian cancer is associated with higher tumor infiltrating T cells and a better prognosis.PloS one · 2012Article
- HLA-DPB1-COL11A2 and three additional xMHC loci are independently associated with RA in a UK cohort.Genes and immunity · 2011Article
- Butyrophilin-like 1 encodes an enterocyte protein that selectively regulates functional interactions with T lymphocytes.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- The PRY/SPRY/B30.2 domain of butyrophilin 1A1 (BTN1A1) binds to xanthine oxidoreductase: implications for the function of BTN1A1 in the mammary gland and other tissues.The Journal of biological chemistry · 2009Article
- Reproducible association with type 1 diabetes in the extended class I region of the major histocompatibility complex.Genes and immunity · 2009Article
- Yin-Yang of costimulation: crucial controls of immune tolerance and function.Immunological reviews · 2009Review
- Stimulation of human CD4⁺ T lymphocytes via TLR3, TLR5 and TLR7/8 up-regulates expression of costimulatory and modulates proliferation.The open microbiology journal · 2009Article
- Efficient subgroup C avian sarcoma and leukosis virus receptor activity requires the IgV domain of the Tvc receptor and proper display on the cell membrane.Journal of virology · 2008Article
- BTNL2, a butyrophilin-like molecule that functions to inhibit T cell activation.Journal of immunology (Baltimore, Md. : 1950) · 2006Article
- Massive apoptosis in lymphoid organs in animal models for primary and secondary progressive multiple sclerosis.The American journal of pathology · 2005Article
- Expression of butyrophilin (Btn1a1) in lactating mammary gland is essential for the regulated secretion of milk-lipid droplets.Proceedings of the National Academy of Sciences of the United States of America · 2004Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
B7-1 and B7-2 are members of the immunoglobulin superfamily (IgSF) and important regulators of T cell-mediated immune responses. Despite sharing only limited sequence identity, B7-1 and B7-2 bind common receptors, CD28 and CTLA-4, on T cells and have similar functional properties. We have found that the extracellular V (ariable)-like domains of B7-1 and B7-2 share significant sequence similarities with 3 major histocompatibility complex (MHC)-encoded members of the IgSF: butyrophilin, myelin/oligodendrocyte glycoprotein, and the chicken MHC molecule, B-G. This raises the question whether there is an evolutionary link between the MHC, which encodes molecules regulating the antigen specificity of T lymphocyte responses, and B7 molecules, which co-stimulate these responses in antigen-nonspecific fashion.
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Registered trials
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