ArticleMolecular and cellular biology1994
A novel synapse-associated noncoding RNA.
Article in Molecular and cellular biology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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Who cites it
23 citing papers in PubMed, 51 citations in OpenAlex.
- Cerebellar microRNA-206 tunes Purkinje neuron firing dynamics to control sensorimotor gating.bioRxiv : the preprint server for biology · 2026Article
- Roles of the canonical myomiRs miR-1, -133 and -206 in cell development and disease.World journal of biological chemistry · 2015Review
- The RNA-centred view of the synapse: non-coding RNAs and synaptic plasticity.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2014Review
- Article
- Normal midbrain dopaminergic neuron development and function in miR-133b mutant mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice.Science (New York, N.Y.) · 2009Article
- MicroRNAs show mutually exclusive expression patterns in the brain of adult male rats.PloS one · 2009Article
- microRNA regulation of synaptic plasticity.Neuromolecular medicine · 2009Review
- MicroRNA-206: the skeletal muscle-specific myomiR.Biochimica et biophysica acta · 2008Review
- Noncoding RNA in development.Mammalian genome : official journal of the International Mammalian Genome Society · 2008Review
- Expression of microRNAs and their precursors in synaptic fractions of adult mouse forebrain.Journal of neurochemistry · 2008Article
- Comparative analysis of genome tiling array data reveals many novel primate-specific functional RNAs in human.BMC evolutionary biology · 2007Article
- Myogenic factors that regulate expression of muscle-specific microRNAs.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
- SKCG-1: a new candidate growth regulatory gene at chromosome 11q23.2 in human sporadic Wilms tumours.British journal of cancer · 2006Article
- MIR-206 regulates connexin43 expression during skeletal muscle development.Nucleic acids research · 2006Article
- LL5beta: a regulator of postsynaptic differentiation identified in a screen for synaptically enriched transcripts at the neuromuscular junction.The Journal of cell biology · 2005Article
- Identification of mammalian microRNA host genes and transcription units.Genome research · 2004Article
- Identification of putative noncoding RNAs among the RIKEN mouse full-length cDNA collection.Genome research · 2003Article
- UM 9(5)h and UM 9(5)p, human and porcine noncoding transcripts with preferential expression in the cerebellum.RNA (New York, N.Y.) · 2002Article
- PCGEM1, a prostate-specific gene, is overexpressed in prostate cancer.Proceedings of the National Academy of Sciences of the United States of America · 2000Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Synaptic nuclei of innervated muscle transcribe acetylcholine receptor (AChR) genes at a much higher level than extrasynaptic nuclei. To isolate candidate synaptic regulatory molecules responsible for the unique transcriptional potential of synaptic nuclei, we have taken a subtractive hybridization approach. Here, we report the cloning and characterization of a novel synapse-associated RNA, 7H4. 7H4 is expressed selectively in the endplate zone of skeletal muscle and is upregulated during early postnatal development and after denervation. Interestingly, the 7H4 gene has no introns, and yet two different-size RNAs with identical polyadenylated 3' ends are generated. Most intriguingly, the nucleotide sequence does not contain any significant open reading frames, suggesting that 7H4 may function as a noncoding RNA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.