Molecular biologic investigations of proto-oncogenes and growth factors in human testicular tumors.

T Strohmeyer

Abstract readReview

In one paragraph

Review in World journal of urology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

1.2field-weighted citation impact, top 20% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 13 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

T StrohmeyerDepartment of Clinical Research and Development Oncology, Schering AG, Berlin, Germany.

Heinrich Heine University Düsseldorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Molecular genetic alterations of known protoncogenes and growth factors, e.g. c-kit and its ligand SCF as well as hst1 and c-myc, are likely to play a role in the development of testicular cancer. In addition, identification and analysis of genes located on the frequently altered chromosome 12 represent an important focus of research. Genetic alterations may occur in a stepwise fashion, as described in other human tumors, leading to the development of the various histologic subtypes of testicular germ cell tumors. The characterization of these alterations are most likely to extend the traditional histopathologic tumor classifications.

Indexed as

Chromosomes, Human, Pair 12Biomarkers, TumorChromosome AberrationsEmbryonal Carcinoma Stem CellsErb-b2 Receptor Tyrosine KinasesErbB ReceptorsFibroblast Growth Factor 3Fibroblast Growth Factor 4Fibroblast Growth FactorsGene AmplificationGene Expression Regulation, NeoplasticGenetic MarkersGerminomaHumansMaleMolecular BiologyBiomarkers, TumorErb-b2 Receptor Tyrosine KinasesErbB ReceptorsFGF3 protein, humanFGF4 protein, humanFibroblast Growth Factor 3Fibroblast Growth Factor 4Fibroblast Growth FactorsGenetic MarkersProtein-Tyrosine KinasesProto-Oncogene ProteinsProto-Oncogene Proteins c-kitProto-Oncogene Proteins c-mycReceptor Protein-Tyrosine KinasesReceptors, Colony-Stimulating FactorRNA, MessengerTransforming Growth Factor alpha

Identifiers

PMID7522081

DOI10.1007/BF00184240

OpenAlexW2027428116

What OpenQuestion holds

Textmetadata

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.