ArticleUrological research1994
Studies on calcium oxalate monohydrate crystallization: influence of inhibitors.
Article in Urological research, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Key Aspects of Myo-Inositol Hexaphosphate (Phytate) and Pathological Calcifications.Molecules (Basel, Switzerland) · 2019Review
- Potential thermodynamic and kinetic roles of phytate as an inhibitor of kidney stone formation: theoretical modelling and crystallization experiments.Urolithiasis · 2019Article
- Urinary pH and renal lithiasis.Urological research · 2012Article
- Urinary glycosaminoglycan excretion in healthy and stone-forming children.Pediatric nephrology (Berlin, Germany) · 1996Article
- A new procedure to evaluate the inhibitory capacity of calcium oxalate crystallization in whole urine.International urology and nephrology · 1995Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A simple model to study calcium oxalate monohydrate (COM) crystallization on different substrates is presented and the action of different potential inhibitors is evaluated and discussed. COM heterogeneous nucleation was assayed on solid surfaces as calcium phosphate, mixtures of mucin with calcium phosphate, and wax. In the presence of a non-protected non-renewed solid surface in contact with normal urine, COM crystal formation could be detected at short intervals (3 h). The most active heterogeneous nucleation capacity corresponded to calcium phosphate. In the presence of 10% mucin, owing to the renewal of the surface layer no COM crystal were detected on the pellet's surface. The study of citrate and pentosan polysulphate (a semisynthetic polysaccharide) on COM heterogeneous nucleation demonstrated some important inhibitory effects when concentration increased and time decreased. Maximum effects were selectively manifested on calcium phosphate surfaces. Only phytic acid at adequate concentration exhibited a total inhibitory capacity of COM formation, even during longer intervals (15 h).
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Registered trials
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