ArticleArchives of dermatological research1994
Expression of c-kit ligand in human keratinocytes.
Article in Archives of dermatological research, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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Who cites it
12 citing papers in PubMed, 49 citations in OpenAlex.
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- A Clinical and Biochemical Evaluation of a Temperature-Controlled Continuous Non-Invasive Radiofrequency Device for the Treatment of Melasma.Annals of dermatology · 2021Article
- Concurrent hand-foot skin reaction and hair depigmentation with sunitinib: report of a case and literature review of kinase inhibitors and blocking antibodies.Indian journal of dermatology · 2014Article
- Sorafenib and sunitinib: A dermatologist's perspective.Indian dermatology online journal · 2014Article
- Role of keratinocytes in the development of vitiligo.Annals of dermatology · 2012Article
- TAK1 regulates SCF expression to modulate PKBα activity that protects keratinocytes from ROS-induced apoptosis.Cell death and differentiation · 2011Article
- A Second Case of Sunitinib-associated Pyoderma Gangrenosum.The Journal of clinical and aesthetic dermatology · 2010Article
- Gain-of-function mutation of KIT ligand on melanin synthesis causes familial progressive hyperpigmentation.American journal of human genetics · 2009Article
- Hand-foot skin reaction increases with cumulative sorafenib dose and with combination anti-vascular endothelial growth factor therapy.Clinical cancer research : an official journal of the American Association for Cancer Research · 2009Article
- Biological characterization of human fibroblast-derived mitogenic factors for human melanocytes.The Biochemical journal · 1998Article
- Familial progressive hyper- and hypopigmentation: a report on a Chinese family and evidence for genetic heterogeneity.Anais brasileiros de dermatologiaArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The c-kit ligand is expressed on tissue-anchored stromal cells. It plays an important role in the development of c-kit-bearing cells, such as haematopoietic cells, germ cells, mast cells and melanocytes. In the present study, we used the reverse transcriptase-mediated polymerase chain reaction (PCR) technique to investigate whether human keratinocytes are able to express c-kit ligand mRNA. Two sets of primers were designed to distinguish two types of c-kit ligand mRNA (full-length type and spliced type). One set was used to amplify an 882-bp DNA fragment from the full-length type, and a 798-bp DNA fragment from the spliced type. Another set was used to amplify a 375-bp DNA fragment from the full-length type only. A cDNA fragment corresponding to the full-length type mRNA was amplified from a cDNA preparation of cultured human keratinocytes as well as from epidermis obtained by the suction blister technique. This result indicates the spontaneous transcription of full-length type mRNA of the c-kit ligand in human keratinocytes.
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