Evidence map›Paper›PMID 7519630›Full record

ArticleJournal of clinical microbiology1994

Use of PCR with feces for detection of Helicobacter pylori infections in patients.

A A van Zwet, J C Thijs, A M Kooistra-Smid, J Schirm, J A Snijder

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical microbiology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 85 citations in OpenAlex.

  1. Non-invasive diagnostic tests for Helicobacter pylori infection.The Cochrane database of systematic reviews · 2018
    Pooled it
  2. Neonatal infection withInfection and immunity · 2025
    Article
  3. Article
  4. Ulcerative Colitis and Its Association with Salmonella Species.Interdisciplinary perspectives on infectious diseases · 2016
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

A A van ZwetRegional Public Health Laboratory, Groningen, The Netherlands.
J C Thijs
A M Kooistra-Smid
J Schirm
J A Snijder
Dialyse Centrum Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PCR was performed for the detection of Helicobacter pylori in feces from 24 patients with proven infections. Several precautions were taken to overcome possible inhibition of PCR with feces. In the first 12 patients, feces were examined shortly after endoscopy. In another group of 12 patients, who were treated during 2 weeks with omeprazole (40 mg each day) to increase gastric pH, feces were examined as well. H. pylori target DNA could not be detected in the stools of any of the 24 infected patients. It was concluded that there was no substantial shedding of H. pylori in feces from either group of patients.

Indexed as

Base SequenceDNA, BacterialDNA PrimersDuodenal UlcerEvaluation Studies as TopicFecesGastritisHelicobacter InfectionsHelicobacter pyloriHumansMolecular Sequence DataPolymerase Chain ReactionRNA, BacterialRNA, Ribosomal, 16SSensitivity and SpecificityStomach UlcerDNA, BacterialDNA PrimersRNA, BacterialRNA, Ribosomal, 16S

Identifiers

PMID7519630
PMCPMC263696
OpenAlexW1894973513

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.