ArticleThe American journal of pathology1994
Microtubule-associated protein tau epitopes are present in fiber lesions in diverse muscle disorders.
Article in The American journal of pathology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 30 citations in OpenAlex.
- Microtubule-associated protein tau in murine kidney: role in podocyte architecture.Cellular and molecular life sciences : CMLS · 2022Article
- Article
- High-Intensity Interval Training Is Associated With Alterations in Blood Biomarkers Related to Brain Injury.Frontiers in physiology · 2018Article
- Repetitive head impact exposure and later-life plasma total tau in former National Football League players.Alzheimer's & dementia (Amsterdam, Netherlands) · 2017Article
- Preliminary Study of Plasma Exosomal Tau as a Potential Biomarker for Chronic Traumatic Encephalopathy.Journal of Alzheimer's disease : JAD · 2016Article
- Tau protein immunoreactivity in muscle fibers with rimmed vacuoles differs from that in regenerating muscle fibers.Acta neuropathologica · 1995Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The microtubule-associated protein tau is a major cytoskeletal protein involved in the neurofibrillary tangles of Alzheimer's disease. Although tau is predominantly a neuronal protein, it has been demonstrated in glia and other nonneuronal cells. We describe the presence of microtubule-associated protein tau epitopes in various muscle fiber lesions in oculopharyngeal and Becker muscular dystrophy, dermatomyositis, central core disease, neurogenic atrophy, and in the recovery phase of an attack of malignant hyperthermia. Western blot demonstrated a 100- to 110-kd tau-immunoreactive protein probably corresponding to 'big tau' as described in peripheral nerves. Tau immunoreactivity in muscle fiber lesions usually co-localized with tubulin, although electron microscopy failed to show an increase in microtubules. Tau and tubulin reactivity also correlated with the presence of desmin and vimentin epitopes. Possible explanations for the presence of tau are briefly discussed.
Indexed as
Identifiers
7518193PMC1887305W2155280727What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.