ReviewDrugs1994
Omega-3 fatty acids. Current status in cardiovascular medicine.
Review in Drugs, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01422317 (Effects of a High-dose Concentrate of n-3 Fatty Acids or Corn Oil Introduced Early After an Acute Myocardial Infarction on Serum Triacylglycerol and High-density Lipoprotein), which is not on this map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of a High-dose Concentrate of n-3 Fatty Acids or Corn Oil Introduced Early After an Acute Myocardial Infarction on Serum Triacylglycerol and High-density Lipoprotein (HDL)- Cholesterol
Who cites it
22 citing papers in PubMed, 136 citations in OpenAlex.
- Increased lipid peroxidation during long-term intervention with high doses of n-3 fatty acids (PUFAs) following an acute myocardial infarction.European journal of clinical nutrition · 2003Trial
- Trial
- Trial
- Multi-omics reveals terpenoid biosynthesis and antioxidant activity at maturity stage in Zanthoxylum armatum DC. fruits.NPJ science of food · 2026Article
- International Society of Sports Nutrition Position Stand: Long-Chain Omega-3 Polyunsaturated Fatty Acids.Journal of the International Society of Sports Nutrition · 2025Review
- Role of saturated and unsaturated fatty acids on dicarbonyl-albumin derived advanced glycation end products in vitro.Amino acids · 2022Article
- Herring Oil and Omega Fatty Acids InhibitFrontiers in microbiology · 2018Article
- The use of fish oil lipid emulsion in the treatment of intestinal failure associated liver disease (IFALD).Nutrients · 2012Review
- Impact of fish oil-based lipid emulsion on serum triglyceride, bilirubin, and albumin levels in children with parenteral nutrition-associated liver disease.Pediatric research · 2009Article
- Hypertension prevention: from nutrients to (fortified) foods to dietary patterns. Focus on fatty acids.Journal of human hypertension · 2005Review
- Naturopathy, pseudoscience, and medicine: myths and fallacies vs truth.MedGenMed : Medscape general medicine · 2004Article
- Blood lipids, fatty acids, diet and lifestyle parameters in adolescents from a region in northern Norway with a high mortality from coronary heart disease.European journal of clinical nutrition · 2002Article
- Antioxidants in exercise nutrition.Sports medicine (Auckland, N.Z.) · 2001Review
- Long-chain n-3 polyunsaturated fatty acids and triacylglycerol metabolism in the postprandial state.Lipids · 1999Review
- Review
- Polyunsaturated fatty acids inhibit T cell signal transduction by modification of detergent-insoluble membrane domains.The Journal of cell biology · 1998Article
- Article
- Residential exposure to plasticizers and its possible role in the pathogenesis of asthma.Environmental health perspectives · 1997Article
- Exposure to the n-3 polyunsaturated fatty acid docosahexaenoic acid impairs alpha 1-adrenoceptor-mediated contractile responses and inositol phosphate formation in rat cardiomyocytes.Naunyn-Schmiedeberg's archives of pharmacology · 1996Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Omega-3 polyunsaturated fatty acids (PUFA) reduce fasting and postprandial triglycerides, decrease platelet and leucocyte reactivity, and may slightly decrease blood pressure. Omega-3 PUFA may also beneficially influence vessel wall characteristics and blood rheology. Furthermore, these compounds have been shown to inhibit ventricular tachyarrhythmias in animals. Omega-3 PUFA may impair fibrinolysis and could lead to increased oxidation of lipoproteins. Potential adverse effects must not be neglected, but should be viewed in light of the beneficial effects of these agents. Clinical studies investigating the effects of dietary omega-3 PUFA in the prevention and treatment of cardiovascular disease (CVD) are beginning to emerge. The results have offered some promise, but further studies are needed to define the role of these agents in CVD. Long term trials and studies using omega-3 PUFA as adjuvants to conventional therapy in patients with coronary artery disease, hyperlipidaemia and hypertension may be of particular interest.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.