ArticleCell and tissue research1994
Nitric oxide synthase-containing nerve fibers and neurons in the genital tract of the female mouse.
Article in Cell and tissue research, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 48 citations in OpenAlex.
- Smooth Muscle Organization and Nerves in the Rat Vagina: A First Look Using Tissue Clearing and Immunolabeling.Annals of biomedical engineering · 2022Article
- Histological and functional aspects of different regions of the rabbit vagina.International journal of impotence research · 2003Article
- Important differences in nitric oxide synthase activity and predominant isoform in reproductive tissues from human and rat.Reproductive biology and endocrinology : RB&E · 2003Article
- Morphological and functional characterization of a rat vaginal smooth muscle sphincter.International journal of impotence research · 2002Article
- Characterization of the non-nitrergic NANC relaxation responses in the rabbit vaginal wall.British journal of pharmacology · 2002Article
- Effects of estrogen on nitric oxide synthase and histological composition in the rabbit clitoris and vagina.International journal of impotence research · 2001Article
- Localization of nitric oxide-related substances in the quail ovary during folliculogenesis.The Histochemical journal · 1999Article
- Impaired ovulation in mice with targeted deletion of the neuronal isoform of nitric oxide synthase.Molecular medicine (Cambridge, Mass.) · 1998Article
- Innervation of vasculature and microvasculature of the human vagina by NOS and neuropeptide-containing nerves.Journal of anatomy · 1996Article
- Histochemistry of nitric oxide synthase in the nervous system.The Histochemical journal · 1995Review
- The distribution and co-localization of immunoreactivity to nitric oxide synthase, vasoactive intestinal polypeptide and substance P within nerve fibres supplying bovine and porcine female genital organs.Cell and tissue research · 1995Article
- Nitroxergic innervation of the human ureterovesical junction.Urological research · 1995Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nitric oxide (NO) is generated intracellularly from L-arginine by the action of the enzyme nitric oxide synthase (NOS). The present investigation demonstrates immunoreactivity against NOS and nicotinamide adenine dinucleotide phosphate (NADPH)-diaphorase activity in nerve cells and fibers of the reproductive system of the female mouse. The density of nerve fibers staining for NOS varied among different genital organs. The ovary and Fallopian tube were devoid of NOS-positive nerves. The uterine horns received sparse innervation by NOS-containing nerve fibers. The most abundant NOergic innervation was found in the uterine cervix and vagina, where the nerve fibers ran parallel to the smooth muscle bundles and beneath the epithelium; they also accompanied intramural blood vessels. The vaginal muscular wall contained single or groups of NOS-reactive nerve cells. Clusters of NOS-containing neurons were located in Frankenhäuser's ganglion at the cervico-vaginal junction. NO may therefore act as a transmitter in the nervous control of the female reproductive tract.
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