ArticleArchives of virology1995
BK virus and a new type of JC virus excreted by HIV-1 positive patients in rural Tanzania.
Article in Archives of virology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 74 citations in OpenAlex.
- Increased frequency of JC virus type 2 and of dual infection with JC virus type 1 and 2 in Italian progressive multifocal leukoencephalopathy patients.Journal of neurovirology · 2001Trial
- The prevalence and isolated subtypes of BK polyomavirus reactivation among patients infected with human immunodeficiency virus-1 in southeastern China.Archives of virology · 2018Article
- Detection and analysis of variants of JC polyomavirus in urine samples from HIV-1-infected patients in China's Zhejiang Province.The Journal of international medical research · 2018Article
- BK nephropathy in the native kidneys of patients with organ transplants: Clinical spectrum of BK infection.World journal of transplantation · 2016Review
- Molecular biology, epidemiology, and pathogenesis of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain.Clinical microbiology reviews · 2012Review
- Evolution of BK virus based on complete genome data.Journal of molecular evolution · 2006Article
- Genotypes of JC virus, DNA of cytomegalovirus, and proviral DNA of human immunodeficiency virus in eyes of acquired immunodeficiency syndrome patients.Journal of neurovirology · 2005Article
- Molecular analysis of JC virus genotypes circulating among the Italian healthy population.Journal of neurovirology · 2003Article
- Analysis of the excreted JC virus strains and their potential oral transmission.Journal of neurovirology · 2003Article
- Role of the environment in the transmission of JC virus.Journal of neurovirology · 2003Review
- Archetype JC virus efficiently replicates in COS-7 cells, simian cells constitutively expressing simian virus 40 T antigen.Journal of virology · 1998Article
- Tubulointerstitial nephritis due to a mutant polyomavirus BK virus strain, BKV(Cin), causing end-stage renal disease.Journal of clinical microbiology · 1998Article
- Asian genotypes of JC virus in Native Americans and in a Pacific Island population: markers of viral evolution and human migration.Proceedings of the National Academy of Sciences of the United States of America · 1997Article
- Typing of urinary JC virus DNA offers a novel means of tracing human migrations.Proceedings of the National Academy of Sciences of the United States of America · 1997Article
- Persistent JC virus (JCV) infection is demonstrated by continuous shedding of the same JCV strains.Journal of clinical microbiology · 1997Article
- Genotype profile of human polyomavirus JC excreted in urine of immunocompetent individuals.Journal of clinical microbiology · 1996Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
Abstract
HIV-1 positive patients from Tanzanian villages near Shirati were examined for urinary excretion of the human polyomaviruses JC and BK using the polymerase chain reaction (PCR). BK virus (BKV) was detected in 11 of 23 individuals tested. The BKV DNA sequences were all closely related to prototype Gardner strain and BKV (DUN). In contrast, a new type of JCV, termed Type 3 [or JCV (Shi)], was identified in seven of these same 23 individuals by comparison with Type 1 and Type 2 sequences of the VP1/intergenic/T antigen region of U.S., European and Asian strains. This suggests that JCV and BKV, although closely related, have different evolutionary histories within the African population. The six BKV regulatory regions amplified all showed the archetypal configuration. However, two of the seven JCV regulatory regions showed rearrangements: a small deletion and an inverted repeat. JCV causes a fatal demyelinating disease, progressive multifocal leukoencephalopathy (PML), in about 5% of AIDS patients in Europe and the U.S.A., but only one case has been reported in Africa. Our results suggest that this rarity of PML is not due to the absence of JCV in the African population.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.