Evidence map›Paper›PMID 7503686›Full record

ArticleArchives of virology1995

Sequence variation in the L1 gene of human papillomavirus type 16 from Africa.

J E Ramesar, E P Rybicki, A L Williamson

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of virology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. From plant virology to vaccinology: The road less travelled.Human vaccines & immunotherapeutics · 2015
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

J E RamesarDepartment of Medical Mircobiology, University of Cape Town Medical School, South Africa.
E P Rybicki
A L Williamson

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 297 bp fragment of the HPV 16 L1 gene was sequenced from 35 isolates originating from normal cervical scrapes, cervical intraepithelial neoplasia biopsies and cervical carcinoma biopsies from South African women. A total of six point mutations that differed from the prototype HPV 16 sequence were detected in various combinations, giving rise to six distinct types of variants. Only one of the isolates had a sequence identical to the prototype. Our results indicate that the HPV L1 gene is conserved and there is no evidence that specific viral HPV L1 variants are associated with specific pathology.

Indexed as

Genes, ViralAmino Acid SequenceAntigens, ViralCarcinomaCervix UteriEpitope MappingFemaleHumansMolecular Sequence DataPapillomaviridaePoint MutationPolymorphism, GeneticUterine Cervical DysplasiaUterine Cervical NeoplasmsViral Structural ProteinsAntigens, ViralViral Structural Proteins

Identifiers

PMID7503686

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.