ArticleMolecular & general genetics : MGG1995
Mutations affecting the mitochondrial genes encoding the cytochrome oxidase subunit I and apocytochrome b of Chlamydomonas reinhardtii.
Article in Molecular & general genetics : MGG, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 47 citations in OpenAlex.
- Cytochrome c oxidase inactivation in Physcomitrium patens reveals that respiration coordinates plant metabolism.The Plant cell · 2025Article
- Recurrent evolutionary switches of mitochondrial cytochrome c maturation systems in Archaeplastida.Nature communications · 2024Article
- Light-independent regulation of algal photoprotection by CONature communications · 2023Article
- Strategies to Study Dark Growth Deficient or Slower Mutants in Chlamydomonas reinhardtii.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Reciprocal regulation of photosynthesis and mitochondrial respiration by TOR kinase inPlant direct · 2019Article
- The Arabidopsis COX11 Homolog is Essential for Cytochrome c Oxidase Activity.Frontiers in plant science · 2015Article
- Divergent functions of the Arabidopsis mitochondrial SCO proteins: HCC1 is essential for COX activity while HCC2 is involved in the UV-B stress response.Frontiers in plant science · 2014Article
- Characterization of an internal type-II NADH dehydrogenase from Chlamydomonas reinhardtii mitochondria.Current genetics · 2012Article
- Paternal inheritance of mitochondria in Chlamydomonas.Journal of plant research · 2010Review
- Complete elimination of maternal mitochondrial DNA during meiosis resulting in the paternal inheritance of the mitochondrial genome in Chlamydomonas species.Protoplasma · 2006Article
- High-efficiency biolistic transformation of Chlamydomonas mitochondria can be used to insert mutations in complex I genes.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
- Shared molecular characteristics of successfully transformed mitochondrial genomes in Chlamydomonas reinhardtii.Plant molecular biology · 2005Article
- Impact of a mutation in the mitochondrial LSU rRNA gene from Chlamydomonas reinhardtii on the activity and the assembly of respiratory-chain complexes.Current genetics · 2004Article
- Photosynthesis and state transitions in mitochondrial mutants of Chlamydomonas reinhardtii affected in respiration.Plant physiology · 2003Article
- Article
- Alteration of dark respiration and reduction of phototrophic growth in a mitochondrial DNA deletion mutant of Chlamydomonas lacking cob, nd4, and the 3' end of nd5.The Plant cell · 1999Article
- Article
- Genetic mapping of mitochondrial markers by recombinational analysis in Chlamydomonas reinhardtii.Molecular & general genetics : MGG · 1995Article
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9 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Mitochondrial mutants of the green alga Chlamydomonas reinhardtii that are inactivated in the cytochrome pathway of respiration have previously been isolated. Despite the fact that the alternative oxidase pathway is still active the mutants have lost the capacity to grow heterotrophically (dark + acetate) and display reduced growth under mixotrophic conditions (light + acetate). In crosses between wild-type and mutant cells, the meiotic progeny only inherit the character transmitted by the mt- parent, which indicates that the mutations are located in the 15.8 kb linear mitochondrial genome. Two new mutants (dum-18 and dum-19) have now been isolated and characterized genetically, biochemically and at the molecular level. In addition, two previously isolated mutants (dum-11 and dum-15) were characterized in more detail. dum-11 contains two types of deleted mitochondrial DNA molecules: 15.1 kb monomers lacking the subterminal part of the genome, downstream of codon 147 of the apocytochrome b (COB) gene, and dimers resulting from head-to-head fusion of asymmetrically deleted monomers (15.1 and 9.5 kb DNA molecules, respectively). As in the wild type, the three other mutants contain only 15.8 kb mitochondrial DNA molecules. dum-15 is mutated at codon 140 of the COB gene, a serine (TCT) being changed into a tyrosine (TAC). dum-18 and dum-19 both inactivate cytochrome c oxidase, as a result of frameshift mutations (addition or deletion of 1 bp) at codons 145 and 152, respectively, of the COX1 gene encoding subunit I of cytochrome c oxidase. In a total of ten respiratory deficient mitochondrial mutants characterized thus far, only mutations located in COB or COX1 have been isolated.(ABSTRACT TRUNCATED AT 250 WORDS)
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