ArticleJournal of muscle research and cell motility1995
Expression of extraocular myosin heavy chain in rabbit laryngeal muscle.
Article in Journal of muscle research and cell motility, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 88 citations in OpenAlex.
- PKNOX2 is associated with formal thought disorder in schizophrenia: a meta-analysis of two genome-wide association studies.Journal of molecular neuroscience : MN · 2012Pooled it
- Research into the physiology of myosins - a personal odyssey.European journal of translational myology · 2025Article
- Developmental, Physiological and Phylogenetic Perspectives on the Expression and Regulation of Myosin Heavy Chains in Craniofacial Muscles.International journal of molecular sciences · 2024Review
- Complex Correlations Between Desmin Content, Myofiber Types, and Innervation Patterns in the Human Extraocular Muscles.Investigative ophthalmology & visual science · 2020Article
- Dysfunction of NaV1.4, a skeletal muscle voltage-gated sodium channel, in sudden infant death syndrome: a case-control study.Lancet (London, England) · 2018Article
- The superfast human extraocular myosin is kinetically distinct from the fast skeletal IIa, IIb, and IId isoforms.The Journal of biological chemistry · 2013Article
- Postnatal changes in the developing rat extraocular muscles.Investigative ophthalmology & visual science · 2011Article
- Immunohistochemical analysis of the effects of cross-innervation of murine thyroarytenoid and sternohyoid muscles.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2010Article
- Functional diversity among a family of human skeletal muscle myosin motors.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Immunohistochemical analysis of laryngeal muscles in normal horses and horses with subclinical recurrent laryngeal neuropathy.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2009Article
- Immunohistochemical analysis of myosin heavy chain expression in laryngeal muscles of the rabbit, cat, and baboon.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2008Article
- Heterogeneity of alpha-cardiac myosin heavy chains in a small marsupial, Antechinus flavipes, and the effect of hypothyroidism on its ventricular myosins.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2008Article
- Developmental changes in ventricular myosin isoenzymes of the tammar wallaby.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2007Article
- Marsupial cardiac myosins are similar to those of eutherians in subunit composition and in the correlation of their expression with body size.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2007Article
- Cross-bridge kinetics of fast and slow fibres of cat jaw and limb muscles: correlations with myosin subunit composition.Journal of muscle research and cell motility · 2007Article
- Myosin isoforms and fibre types in jaw-closing muscles of Australian marsupials.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2006Article
- Unloaded shortening velocity and myosin heavy chain variations in human laryngeal muscle fibers.The Annals of otology, rhinology, and laryngology · 2002Article
- Contractile properties and myosin heavy chain isoform composition in single fibre of human laryngeal muscles.Journal of muscle research and cell motility · 2002Article
- Influence of early postnatal cold exposure on myofiber maturation in pig skeletal muscle.Journal of muscle research and cell motility · 2001Article
- Jaw-closing muscles of kangaroos express alpha-cardiac myosin heavy chain.Journal of muscle research and cell motility · 2000Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The intrinsic laryngeal muscles of mammals are functionally heterogeneous, some of these muscles (e.g. the thyroarytenoid) contract extremely rapidly, like extraocular muscle, whilst others (e.g. the cricothyroid) contract as fast as limb fast muscle. The extraordinarily rapid contraction speed of extraocular muscles is associated with a fast myosin not found in limb muscles. In this work we explored the possibility that the thyroarytenoid muscle may also express this extraocular-specific fast myosin by raising a monoclonal antibody (mab 4A6) against its heavy chain. Electrophoretic separation of native isomyosins revealed that both the extraocular and the thyroarytenoid have two similar bands migrating ahead of bands found in limb fast or cricothyroid myosins. These two bands bound mab 4A6. The thyroarytenoid muscle can be divided into two divisions, a vocalis division which is important in phonation and an external division which functions in closing the glottis. Fibres in the vocalis are heterogeneous, some stain with mab 4A6, whilst others stain with mabs against limb myosin heavy chains. Fibres in the external division stain almost homogeneous with mab 4A6. The immunohistochemical staining pattern in the cricothyroid muscle resembled that of fast limb muscle: no fibres stained with mab 4A6. Thus, the high speed of contraction of the thyroarytenoid is associated with the same myosin heavy chain found in extraocular muscles, this characteristic is presumably an evolutionary adaptation for rapid closure of the glottis to enhance airway defense mechanisms.
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