ArticleAnnals of the rheumatic diseases1995
Lp(a) lipoprotein levels as a predictor of risk for thrombogenic events in patients with Behçet's disease.
Article in Annals of the rheumatic diseases, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- A systematic review and meta-analysis of the association between the D-dimer and rheumatic diseases.Immunity, inflammation and disease · 2024Pooled it
- Lower total cholesterol and HDL-C levels are associated with increased risk of Behçet's disease in a prospective nationwide Korean study.Scientific reports · 2025Article
- Evaluation of atherogenic laboratory markers in Behçet's disease patients with vascular involvement.Archives of medical science : AMS · 2020Article
- Serum Lipid, Lipoprotein and Oxidatively Modified Low Density Lipoprotein Levels in Active or Inactive Patients with Behçet's Disease.Indian journal of dermatology · 2012Article
- Combined thrombophilic factors increase the risk of recurrent thrombotic events in Behcet's disease.Clinical rheumatology · 2010Article
- Behçet's Disease as a Model of Venous Thrombosis.The open cardiovascular medicine journal · 2010Article
- Serum paraoxonase activity is decreased in the active stage of Behçet's disease.The British journal of ophthalmology · 2004Article
- Behçet's disease and thrombophilia.Annals of the rheumatic diseases · 2001Review
- Clinical implications of elevated lipoprotein(a).Current atherosclerosis reports · 2001Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate whether plasma levels of Lp(a) lipoprotein (Lp(a)) are predictors of defective fibrinolytic activity, leading to thrombosis, in patients with Behçet's disease.
methodsPlasma Lp(a) was measured by enzyme linked immunosorbent assay, lipids and lipoproteins by enzymatic methods, and apolipoproteins A-I and B, fibrinogen (turbidimetric method), tissue plasminogen activator (t-PA), plasminogen activator inhibitor-1 (PAI-1), and D-dimer levels by enzyme immunoassay. Their levels and interactions were evaluated in 33 patients with Behçet's disease (including five with thrombotic complications) and 30 healthy control subjects.
resultsPlasma Lp(a) concentration was significantly greater in the patients than in controls. Nine patients (27%) had levels > 0.30 microgram. There was no correlation between Lp(a) and other lipids and lipoproteins apart from apolipoprotein B. Lp(a) showed inverse correlation with t-PA (r = -0.34, p < 0.05) and D-dimer (r = 0.35, p < 0.05). Patients with thrombotic complications had significantly greater Lp(a) and PAI-1, and lower D-dimer concentrations than control subjects.
conclusionsMeasurement of plasma Lp(a) levels in patients with Behçet's disease may provide useful information regarding the potential development of thrombotic events, because of its possible role in defective fibrinolysis.
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