ArticleJournal of virology1995
Posttranslational signal peptidase cleavage at the flavivirus C-prM junction in vitro.
Article in Journal of virology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- The Dynamic Landscape of Capsid Proteins and Viral RNA Interactions in Flavivirus Genome Packaging and Virus Assembly.Pathogens (Basel, Switzerland) · 2024Review
- SPCS1-Dependent E2-p7 processing determines HCV Assembly efficiency.PLoS pathogens · 2022Article
- Review
- Article
- Internal ribosome entry site-based attenuation of a flavivirus candidate vaccine and evaluation of the effect of beta interferon coexpression on vaccine properties.Journal of virology · 2014Article
- NS2B/3 proteolysis at the C-prM junction of the tick-borne encephalitis virus polyprotein is highly membrane dependent.Virus research · 2012Article
- Extension of flavivirus protein C differentially affects early RNA synthesis and growth in mammalian and arthropod host cells.Journal of virology · 2009Article
- An internal signal sequence directs intramembrane proteolysis of a cellular immunoglobulin domain protein.The Journal of biological chemistry · 2008Article
- Functional analysis of potential carboxy-terminal cleavage sites of tick-borne encephalitis virus capsid protein.Journal of virology · 2008Article
- Uncleaved NS2-3 is required for production of infectious bovine viral diarrhea virus.Journal of virology · 2004Article
- Inefficient signalase cleavage promotes efficient nucleocapsid incorporation into budding flavivirus membranes.Journal of virology · 2004Article
- Folding and dimerization of tick-borne encephalitis virus envelope proteins prM and E in the endoplasmic reticulum.Journal of virology · 2002Article
- Mutations in the yellow fever virus nonstructural protein NS2A selectively block production of infectious particles.Journal of virology · 2002Article
- Alpha-glucosidase inhibitors reduce dengue virus production by affecting the initial steps of virion morphogenesis in the endoplasmic reticulum.Journal of virology · 2000Article
- Mutagenesis of the NS2B-NS3-mediated cleavage site in the flavivirus capsid protein demonstrates a requirement for coordinated processing.Journal of virology · 1999Article
- Encapsidation of the flavivirus kunjin replicon RNA by using a complementation system providing Kunjin virus structural proteins in trans.Journal of virology · 1998Article
- Signal peptidase cleavage at the flavivirus C-prM junction: dependence on the viral NS2B-3 protease for efficient processing requires determinants in C, the signal peptide, and prM.Journal of virology · 1998Article
- Upregulation of signalase processing and induction of prM-E secretion by the flavivirus NS2B-NS3 protease: roles of protease components.Journal of virology · 1997Article
- Human isolates of dengue type 1 virus induce apoptosis in mouse neuroblastoma cells.Journal of virology · 1996Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have investigated the cleavages at the flavivirus capsid-prM protein junction in vitro. When expressed in the absence of the flavivirus proteinase, capsid and prM, which are separated by an internal signal sequence, exist as a membrane-spanning precursor protein. Here we show the induction of posttranslational signal peptidase cleavage of prM by trypsin cleavage of a cytoplasmic region of this precursor protein.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.