Evidence map›Paper›PMID 7491558›Full record

ArticleThorax1995

Relationship between cells obtained by bronchoalveolar lavage and survival in idiopathic pulmonary fibrosis.

K A Boomars, S S Wagenaar, P G Mulder, H van Velzen-Blad, J M van den Bosch

Abstract read
In one paragraph

Article in Thorax, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Prognosis of idiopathic pulmonary fibrosis without anti-fibrotic therapy: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2020
    Pooled it
  2. Bronchoalveolar lavage and response to cyclophosphamide in scleroderma interstitial lung disease.American journal of respiratory and critical care medicine · 2008
    Trial
  3. Article
  4. T Cell Receptor Sharing in Hypersensitivity Pneumonitis.Computational and structural biotechnology journal · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Immune dysregulation as a driver of idiopathic pulmonary fibrosis.The Journal of clinical investigation · 2021
    Review
  10. Review
  11. Independent Clinical Factors Relevant to Prognosis of Patients with Idiopathic Pulmonary Fibrosis.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  12. Article
  13. Cellular interactions in the pathogenesis of interstitial lung diseases.European respiratory review : an official journal of the European Respiratory Society · 2015
    Review
  14. Genetic susceptibility to interstitial pulmonary fibrosis in mice induced by vanadium pentoxide (V2O5).FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2014
    Article
  15. Article
  16. Article
  17. Review
  18. The clinical utility of bronchoalveolar lavage in diffuse parenchymal lung disease.European respiratory review : an official journal of the European Respiratory Society · 2010
    Review
  19. Article
  20. Early interstitial lung disease in familial pulmonary fibrosis.American journal of respiratory and critical care medicine · 2007
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

K A BoomarsDepartment of Pulmonology, St Antonius Hospital, Nieuwegein, The Netherlands.
S S Wagenaar
P G Mulder
H van Velzen-Blad
J M van den Bosch

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relationship between cell types in bronchoalveolar lavage (BAL) fluid and the clinical course of patients with idiopathic pulmonary fibrosis (IPF) has been the subject of several studies. However, the results of these studies are not conclusive. The aim of this study was to investigate the relationship between the absolute and relative cell numbers in BAL fluid from patients with IPF and their survival.

methodsResults obtained from the initial BAL fluid analyses of all histologically proven cases of IPF (n = 49) were selected retrospectively. Cox's proportional hazards survival analysis was used for estimating the relationship between absolute and relative cell numbers and survival.

resultsA negative relationship was found between both the absolute numbers and percentages of eosinophils in BAL fluid samples and survival. No such relationship was demonstrated for the absolute numbers or the percentages of any other cell type.

conclusionsAlthough this study has restrictions, these findings suggest a negative relationship between the absolute numbers and percentages of eosinophils in BAL fluid samples and survival in patients with IPF.

Indexed as

EosinophilsAdultAgedBronchoalveolar Lavage FluidFemaleFollow-Up StudiesHumansLeukocyte CountMaleMiddle AgedProportional Hazards ModelsPulmonary FibrosisSmokingSurvival Analysis

Identifiers

PMID7491558
PMCPMC475023

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.