ArticleJournal of clinical pathology1995
Malignant mesothelioma of the pleura: interobserver variability.
Article in Journal of clinical pathology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
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- Detecting cell types and densities in the tumor microenvironment improves prognostic risk assessment for breast cancer.Biomolecules & biomedicine · 2024Article
- Mapping the landscape of histomorphological cancer phenotypes using self-supervised learning on unannotated pathology slides.Nature communications · 2024Article
- State-of-the-Art of Breast Cancer Diagnosis in Medical Images via Convolutional Neural Networks (CNNs).Journal of healthcare informatics research · 2023Review
- The Italian Experience in the Development of Mesothelioma Registries: A Pathway for Other Countries to Address the Negative Legacy of Asbestos.International journal of environmental research and public health · 2023Article
- Organoids revealed: morphological analysis of the profound next generation in-vitro model with artificial intelligence.Bio-design and manufacturing · 2023Review
- Deep learning in digital pathology image analysis: a survey.Frontiers of medicine · 2020Review
- Histopathological imaging database for oral cancer analysis.Data in brief · 2020Article
- Deep learning techniques for detecting preneoplastic and neoplastic lesions in human colorectal histological images.Oncology letters · 2019Article
- A Novel Digital Score for Abundance of Tumour Infiltrating Lymphocytes Predicts Disease Free Survival in Oral Squamous Cell Carcinoma.Scientific reports · 2019Article
- Assessing the Impact of Color Normalization in Convolutional Neural Network-Based Nuclei Segmentation Frameworks.Frontiers in bioengineering and biotechnology · 2019Article
- Article
- New morphological features for grading pancreatic ductal adenocarcinomas.BioMed research international · 2013Article
- How "objective" are psychiatric diagnoses?: (guess again).Psychiatry (Edgmont (Pa. : Township)) · 2007Article
- Increased risk of malignant mesothelioma of the pleura after residential or domestic exposure to asbestos: a case-control study in Casale Monferrato, Italy.Environmental health perspectives · 2001Article
- Pleural mesothelioma surveillance: validity of cases from a tumour registry.Canadian respiratory journalArticle
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo assess the consistency of histopathological diagnosis of pleural malignant mesothelioma by estimating interobserver agreement between five pathologists.
methodsEighty eight histological sets pertaining to original diagnoses of pleural malignant mesothelioma were reviewed separately by each pathologist. Diagnostic likelihood was graded as definite (A), probable (B), possible (C), improbable (D), and definitely not (E) malignant mesothelioma. The following indexes were estimated: observed proportion of agreement (Po), kappa statistics and proportion of agreement for "positive" (Ppos) and "negative" (Pneg) diagnoses.
resultsSixty cases (68.2%) were rated by at least three reviewers as A or B and by none of the others as D or E. Five (5.7%) were rated by at least two reviewers as D or E and by none of the others as A or B. Nine (10.2%) showed a serious disagreement, rated A or B and D or E. Agreement for sets obtained at necropsy/surgery (median kappa w = 0.57) was similar to that for endoscopic material (median kappa w = 0.54). Agreement was poor on material obtained by needle biopsy (median kappa w = 0.21). The median value of Ppos varied between 0.94 (necropsy/surgery) and 0.67 (needle biopsy) and that of Pneg between 0.78 (necropsy/surgery) and 0.34 (unspecified biopsy). Interobserver agreement on histological typing was good overall (median kappa = 0.59).
conclusionsOf the original histological diagnoses, 70% were consistently reproduced through panel review. Most indexes of agreement between pathologists ranged from poor (needle biopsy) to moderate (necropsy/surgery). Agreement in confirming malignant mesothelioma was greater than that regarding exclusion of this diagnosis. Of the cases finally considered to have malignant mesothelioma, the reproducibility of histological typing was relatively satisfactory.
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