Evidence map›Paper›PMID 7486941›Full record

ArticleAntimicrobial agents and chemotherapy1995

Liposomal amphotericin B therapy of murine histoplasmosis.

J R Graybill, R Bocanegra

Open access · greenAbstract readComparative Study
In one paragraph

Article in Antimicrobial agents and chemotherapy, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Extended Dosing Regimens for Fungal Prophylaxis.Clinical microbiology reviews · 2019
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

J R GraybillDepartment of Medicine, University of Texas Health Science Center at San Antonio, USA.
R Bocanegra
The University of Texas Health Science Center at San Antonio · US

Funding

PHS HHS N0I-A1-25141
6 · The paper itself

Abstract

Liposomal amphotericin B (AmBisome) was compared with amphotericin B deoxycholate for the treatment of disseminated murine histoplasmosis. Liposomal amphotericin B was well tolerated and, milligram for milligram, was as potent as amphotericin B deoxycholate.

Indexed as

Amphotericin BAnimalsAntifungal AgentsColony Count, MicrobialDrug CarriersHistoplasmosisImmunosuppression TherapyKidneyLiposomesMiceMice, Inbred BALB CSpleenAmphotericin BAntifungal AgentsDrug CarriersLiposomes

Identifiers

PMID7486941
PMCPMC162848
OpenAlexW1990653089

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.