ArticleProceedings of the National Academy of Sciences of the United States of America1995
Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 40 citations in OpenAlex.
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- Genome-Wide DNA Alterations in X-Irradiated Human Gingiva Fibroblasts.International journal of molecular sciences · 2020Article
- Progress and prospects of engineered sequence-specific DNA modulating technologies for the management of liver diseases.World journal of hepatology · 2015Review
- An evolutionary arms race between KRAB zinc-finger genes ZNF91/93 and SVA/L1 retrotransposons.Nature · 2014Article
- Rapid sequence and expression divergence suggest selection for novel function in primate-specific KRAB-ZNF genes.Molecular biology and evolution · 2010Article
- Article
- Estimating the phylogeny and divergence times of primates using a supermatrix approach.BMC evolutionary biology · 2009Article
- Human heterochromatin proteins form large domains containing KRAB-ZNF genes.Genome research · 2006Article
- Evolutionary expansion and divergence in the ZNF91 subfamily of primate-specific zinc finger genes.Genome research · 2006Article
- A comprehensive catalog of human KRAB-associated zinc finger genes: insights into the evolutionary history of a large family of transcriptional repressors.Genome research · 2006Article
- Mutations in PRKCSH cause isolated autosomal dominant polycystic liver disease.American journal of human genetics · 2003Article
- Chromosomal location of fifteen unique mouse KRAB-containing zinc finger loci.Mammalian genome : official journal of the International Mammalian Genome Society · 1996Article
- Perspectives on zinc finger protein function and evolution--an update.Molecular biology reports · 1994Review
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10 authors at 2 institutions in 1 country.
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Abstract
The ZNF91 gene family, a subset of the Krüppel-associated box (KRAB)-containing group of zinc finger genes, comprises more than 40 loci; most reside on human chromosome 19p12-p13.1. We have examined the emergence and evolutionary conservation of the ZNF91 family. ZNF91 family members were detected in all species of great apes, gibbons, Old World monkeys, and New World monkeys examined but were not found in prosimians or rodents. In each species containing the ZNF91 family, the genes were clustered at one major site, on the chromosome(s) syntenic to human chromosome 19. To identify a putative "founder" gene, > 20 murine KRAB-containing zinc finger protein (ZFP) cDNAs were randomly cloned, but none showed sequence similarity to the ZNF91 genes. These observations suggest that the ZNF91 gene cluster is a derived character specific to Anthropoidea, resulting from a duplication and amplification event some 55 million years ago in the common ancestor of simians. Although the ZNF91 gene cluster is present in all simian species, the sequences of the human ZNF91 gene that confer DNA-binding specificity were conserved only in great apes, suggesting that there is not a high selective pressure to maintain the DNA targets of these proteins during evolution.
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