ReviewNaunyn-Schmiedeberg's archives of pharmacology1995
Classification of alpha 1-adrenoceptor subtypes.
Review in Naunyn-Schmiedeberg's archives of pharmacology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 179 citations in OpenAlex.
- Cardiac and Vascular αCells · 2020Pooled it
- Pooled it
- Differential vascular alpha1-adrenoceptor antagonism by tamsulosin and terazosin.British journal of clinical pharmacology · 1999Trial
- Radioreceptor assay analysis of tamsulosin and terazosin pharmacokinetics.British journal of clinical pharmacology · 1998Trial
- A bibliometric study of the most-cited research articles and reviews in Naunyn-Schmiedeberg's Archives of Pharmacology (1969-2024).Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Functional characterization of the αFrontiers in pharmacology · 2025Article
- 17β-Estradiol Concentration and Direct βAnnals of neurosciences · 2022Article
- Pharmacologically distinct phenotypes of α1B -adrenoceptors: variation in binding and functional affinities for antagonists.British journal of pharmacology · 2014Article
- α1-Adrenoceptors and muscarinic receptors in voiding function - binding characteristics of therapeutic agents in relation to the pharmacokinetics.British journal of clinical pharmacology · 2011Review
- The α1-adrenergic receptors: diversity of signaling networks and regulation.Journal of receptor and signal transduction research · 2010Review
- Pharmacokinetics and pharmacodynamics of tamsulosin in its modified-release and oral controlled absorption system formulations.Clinical pharmacokinetics · 2010Review
- Apoptosis induction by doxazosin and other quinazoline alpha1-adrenoceptor antagonists: a new mechanism for cancer treatment?Naunyn-Schmiedeberg's archives of pharmacology · 2009Article
- Gene expressions and mechanical functions of α1-adrenoceptor subtypes in mouse ureter.World journal of urology · 2009Article
- Characterization of the alpha1-adrenoceptor subtype mediating contractions of the pig internal anal sphincter.British journal of pharmacology · 2008Article
- Identification of the alpha1L-adrenoceptor in rat cerebral cortex and possible relationship between alpha1L- and alpha1A-adrenoceptors.British journal of pharmacology · 2008Article
- Comparison of three radioligands for the labelling of human beta-adrenoceptor subtypes.Naunyn-Schmiedeberg's archives of pharmacology · 2006Article
- Formalin hindpaw injection induces changes in the [3H]prazosin binding to alpha1-adrenoceptors in specific regions of the mouse brain and spinal cord.Journal of neural transmission (Vienna, Austria : 1996) · 2005Article
- Alpha-1D adrenoceptors are involved in reserpine-induced supersensitivity of rat tail artery.British journal of pharmacology · 2004Article
- Alpha-1 adrenoceptors: evaluation of receptor subtype-binding kinetics in intact arterial tissues and comparison with membrane binding.British journal of pharmacology · 2004Article
- Functional characterisation of alpha(1)-adrenoceptors in denervated rat vas deferens.Naunyn-Schmiedeberg's archives of pharmacology · 2003Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
Abstract
Two alpha 1-adrenoceptor subtypes (alpha 1A and alpha 1B) have been detected in various tissues by pharmacological techniques, and three distinct cDNAs encoding alpha 1-adrenoceptor subtypes have been cloned. The profile of an increasing number of subtype-selective compounds at cloned and endogenous receptors recently has facilitated alignment between cloned and pharmacologically defined alpha 1-adrenoceptor subtypes. Thus, alpha 1a-adrenoceptors (previously designated alpha 1c), alpha 1b-adrenoceptors and alpha 1d-adrenoceptors (previously designated alpha 1a, alpha 1d or alpha 1a/d) are now recognized. Since the alpha 1d-adrenoceptor shares characteristics with both alpha 1A- and alpha 1B-adrenoceptors, tissues previously reported to express alpha 1A- and/or alpha 1B-adrenoceptors may additionally contain alpha 1d-adrenoceptors. This article reviews the features of all three subtypes and discusses possible pitfalls in their pharmacological identification.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.