ArticleImmunology1981
The number and affinity of IgE receptors on dispersed human lung mast cells.
Article in Immunology, 1981. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 33 citations in OpenAlex.
- Regulation of Trafficking and Signaling of the High Affinity IgE Receptor by FcεRIβ and the Potential Impact of FcεRIβ Splicing in Allergic Inflammation.International journal of molecular sciences · 2022Review
- Article
- Management of allergy transfer upon solid organ transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2020Review
- A spatio-temporal model reveals self-limiting FcRoyal Society open science · 2018Article
- Half-life of IgE in serum and skin: Consequences for anti-IgE therapy in patients with allergic disease.The Journal of allergy and clinical immunology · 2017Review
- Exon skipping of FcεRIβ eliminates expression of the high-affinity IgE receptor in mast cells with therapeutic potential for allergy.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Potential effector and immunoregulatory functions of mast cells in mucosal immunity.Mucosal immunology · 2015Review
- Article
- Saturation of immunoglobulin E (IgE) binding sites by polyclonal IgE does not explain the protective effect of helminth infections against atopy.Infection and immunity · 2005Article
- Chronic Urticaria : Expanding the Autoimmune Kaleidoscope.Medical journal, Armed Forces India · 2004Article
- An overview of chronic urticaria.Clinical reviews in allergy & immunology · 2002Review
- Pharmacological studies of pulmonary anaphylaxis in vitro: a review.Agents and actions · 1985Review
- An introduction to allergic disease.Journal of the Royal College of Physicians of London · 1985Article
- Development of transient peanut allergy following lung transplantation: a case report.Canadian respiratory journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mast cells obtained by fragmentation of human lung tissue retained the capacity to bind IgE and to respond to immunological challenge. Direct binding studies with radiolabelled IgE enabled quantification of binding parameters of the reaction between IgE and its receptor on human mast cells. The average equilibrium constant was estimated as 1.0 x 10(8) M -1 and the average number of IgE receptors per mast cell as 1.3 x 10(5).
Indexed as
Identifiers
7319562PMC1554998W134640704What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.