ArticleGut1982
Changes in plasma half-life and clearance of 3H-25-hydroxyvitamin D3 in patients with intestinal malabsorption.
Article in Gut, 1982. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 47 citations in OpenAlex.
- The optimal dosage regimen of vitamin D supplementation for correcting deficiency in adolescents: a pilot randomized controlled trial.European journal of clinical nutrition · 2018Trial
- The Effect of a Gluten-Free Diet on Vitamin D Metabolism in Celiac Disease: The State of the Art.Metabolites · 2023Review
- Review
- Predictors of 25(OH)D half-life and plasma 25(OH)D concentration in The Gambia and the UK.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015Article
- Regulation of calcitriol biosynthesis and activity: focus on gestational vitamin D deficiency and adverse pregnancy outcomes.Nutrients · 2015Review
- Determination of optimal cholecalciferol treatment in renal transplant recipients using a population pharmacokinetic approach.European journal of clinical pharmacology · 2013Article
- Plasma appearance and disappearance of an oral dose of 25-hydroxyvitamin D2 in healthy adults.The British journal of nutrition · 2012Article
- Vitamin D deficiency and toxicity in chronic kidney disease: in search of the therapeutic window.Pediatric nephrology (Berlin, Germany) · 2010Review
- Privational rickets: a modern perspective.Journal of the Royal Society of Medicine · 1994Article
- Laboratory assessment of inflammatory bowel disease.Digestive diseases and sciences · 1987Review
- Biliary excretion of radioactivity after intravenous administration of [3H]25-hydroxyvitamin D3 in man.Digestive diseases and sciences · 1986Article
- Article
- Nutritional disturbances in Crohn's disease.Postgraduate medical journal · 1983Review
- Thoughts on the aetiology of vitamin D deficiency in Asians.Postgraduate medical journal · 1983Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The plasma disappearance of intravenously administered tracer doses of tritium-labelled 25-hydroxyvitamin D3 (25OHD3) wa studied in six normal subjects and in 15 patients with intestinal malabsorption. The plasma half-life was significantly shorter and the clearance rate significantly greater in the group with malabsorption compared with the controls. One explanation for this increased elimination could be interruption of an enterohepatic circulation of 25OHD occurring in subjects with malabsorption and such a mechanism could account for the loss of endogenous vitamin D in these patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.