Evidence map›Paper›PMID 7083641›Full record

ArticleClinical and experimental immunology1982

Human eosinophils and parasitic diseases. II. Characterization of two cell fractions isolated at different densities.

C De Simone, G Donneli, D Meli, F Rosati, F Sorice

Open access · greenAbstract read
In one paragraph

Article in Clinical and experimental immunology, 1982. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 72 citations in OpenAlex.

  1. Article
  2. Eosinophils: a review.Veterinary research communications · 1992
    Review
  3. Article
  4. Article
  5. Hypodense eosinophils and interleukin 5 activity in the blood of patients with the eosinophilia-myalgia syndrome.Proceedings of the National Academy of Sciences of the United States of America · 1990
    Article
  6. Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

C De Simone
G Donneli
D Meli
F Rosati
F Sorice
Fondazione Santa Lucia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new procedure, based on centrifugation through multiple discontinuous gradients of polyvinylpyrrolidone-coated silica particles has been developed for the separation of almost pure eosinophils from blood samples of healthy donors. When this technique is employed for the purification of eosinophils from the peripheral blood of patients with parasitic diseases, two cell fractions almost pure in eosinophil granulocytes are harvested at different densities. Preliminary results, concerning the characterization of these cell fractions, indicate that in the terms of detectable membrane receptors and K cell activity, two distinct eosinophil subpopulations can be recognized.

Indexed as

AmebiasisAnimalsCell SeparationCentrifugation, Density GradientEosinophiliaEosinophilsFilariasisHookworm InfectionsHumansRabbitsRosette FormationSchistosomiasisSheepTrichinellosis

Identifiers

PMID7083641
PMCPMC1536584
OpenAlexW2407376086

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.