ArticleAnatomy and embryology1980
Immunohistochemical localization of serotonin nerve terminals in the lateral entorhinal cortex of the rat: demonstration of two separate patterns of innervation from the midbrain raphe.
Article in Anatomy and embryology, 1980. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 44 citations in OpenAlex.
- Serotonergic modulation of Neural activities in the entorhinal cortex.International journal of physiology, pathophysiology and pharmacology · 2012Article
- Coexpression of serotonin and nitric oxide in the raphe complex: cortical versus subcortical circuit.Anatomical record (Hoboken, N.J. : 2007) · 2010Article
- Functional interrelations between nucleus raphé dorsalis and nucleus raphé medianus: a dual probe microdialysis study of glutamate-stimulated serotonin release.Brain research bulletin · 2009Article
- p-Chloroamphetamine (PCA), 3,4-methylenedioxy-methamphetamine (MDMA) and d-fenfluramine pretreatment attenuates d-fenfluramine-evoked release of 5-HT in vivo.Psychopharmacology · 1994Article
- Localization of serotonin in the hypothalamus and the mesencephalon of the guinea-pig. An immunohistochemical study using monoclonal antibodies.Cell and tissue research · 1985Article
- Immunohistochemical demonstration of the distribution of serotonin neurons in the brainstem of the rat and cat.Cell and tissue research · 1982Article
- The distribution and orientation of serotonin fibers in the entorhinal and other retrohippocampal areas. An immunohistochemical study with anti-serotonin antibodies in the rats brain.Anatomy and embryology · 1981Article
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Authors and funding
4 authors at 3 institutions in 3 countries.
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Abstract
The distribution of serotonin (5-hydroxytryptamine, 5HT) containing nerve terminals in the lateral entorhinal cortex (LEC) has been studied using antibodies against 5-HT in combination with fluorescence histochemistry. Thin, varicose, branching fibers were found to be distributed in a relatively even, diffuse pattern throughout all layers of the LEC. The largest amount of this type of 5HT innervation was in Layer I. This diffuse pattern of 5-HT terminals was supplemented by a dense network of 5HT terminals restricted to Layer III of a small (approximately 1 mm) strip of the LEC. The fibers in this layer were thicker and more convoluted and contained larger varicosities than fibers in any other layer. The existence of a distinct innervation by 5-HT terminals of only a small portion of the LEC demonstrates a hitherto unrecognized and important principle of heterogeneity in 5-HT innervation of cortex. It suggests that 5-5HT neurons in the raphe can selectively influence specific, narrow regions of the lateral perforant path system, which, in turn, affect the intrinsic hippocampal circuits.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.