Evidence map›Paper›PMID 6973280›Full record

ArticleThe American journal of pathology1981

IgA glomerular deposits in experimental cirrhosis.

A A Gormly, P S Smith, A E Seymour, A R Clarkson, A J Woodroffe

Open access · greenAbstract read
In one paragraph

Article in The American journal of pathology, 1981. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Immunopathogenesis of experimental IgA nephropathy.Springer seminars in immunopathology · 1994
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. [Alcohol and IgA in the kidney].Klinische Wochenschrift · 1985
    Article
  11. Article
  12. Mesangial IgA nephropathies--steady progress.The Western journal of medicine · 1984
    Article
  13. Article
  14. Article
  15. Article
  16. Mesangial IgA nephritis.Springer seminars in immunopathology · 1982
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

A A Gormly
P S Smith
A E Seymour
A R Clarkson
A J Woodroffe

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lewis rats rendered cirrhotic by the administration of carbon tetrachloride developed mesangial and glomerular capillary wall deposits of immunoglobulins (especially IgA) and complement. These rats also had circulating immune complexes and markedly elevated serum IgA concentrations. The model suggests that defective hepatic sequestration of circulating IgA polymers and immune complexes may be responsible for the glomerular deposits. A similar mechanism may account for the high incidence of glomerulonephritis in patients with alcoholic cirrhosis.

Indexed as

Immunoglobulin AAnimalsAntigen-Antibody ComplexAscitesImmunoglobulin MKidney GlomerulusLiver Cirrhosis, ExperimentalMaleRatsRats, Inbred LewSplenomegalyTesticular DiseasesAntigen-Antibody ComplexImmunoglobulin AImmunoglobulin M

Identifiers

PMID6973280
PMCPMC1903743
OpenAlexW340560202

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.