ArticleProceedings of the National Academy of Sciences of the United States of America1982
Isolation and characterization of rat skeletal muscle and cytoplasmic actin genes.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1982. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 74 citations in OpenAlex.
- Farewell to Professor David Yaffe - A pillar of the myogenesis field.European journal of translational myology · 2020Article
- Extinction of Oct-3/4 gene expression in embryonal carcinoma x fibroblast somatic cell hybrids is accompanied by changes in the methylation status, chromatin structure, and transcriptional activity of the Oct-3/4 upstream region.Molecular and cellular biology · 1993Article
- Induction of matrix Gla protein synthesis during prolonged 1,25-dihydroxyvitamin D3 treatment of osteosarcoma cells.Calcified tissue international · 1990Article
- Extinction of Ig genes expression in myeloma x fibroblast somatic cell hybrids is accompanied by repression of the oct-2 gene encoding a B-cell specific transcription factor.The EMBO journal · 1990Article
- DNA rearrangement of a homeobox gene in myeloid leukaemic cells.The EMBO journal · 1988Article
- The down-regulation of the chicken cytoplasmic beta actin during myogenic differentiation does not require the gene promoter but involves the 3' end of the gene.Nucleic acids research · 1988Article
- Control of hematopoietic cell growth regulators during mouse fetal development.Molecular and cellular biology · 1987Article
- Extinction of expression of immunoglobulin genes in myeloma X fibroblast somatic cell hybrids.Molecular and cellular biology · 1987Article
- Complete sequence of a bovine type I cytokeratin gene: conserved and variable intron positions in genes of polypeptides of the same cytokeratin subfamily.The EMBO journal · 1985Article
- Mouse testes contain two size classes of actin mRNA that are differentially expressed during spermatogenesis.Molecular and cellular biology · 1985Article
- Structure of a gene for the human epidermal 67-kDa keratin.Proceedings of the National Academy of Sciences of the United States of America · 1985Article
- Divergence and differential expression of soybean actin genes.The EMBO journal · 1985Article
- Characterization of bovine keratin genes: similarities of exon patterns in genes coding for different keratins.The EMBO journal · 1984Article
- Structure of a human smooth muscle actin gene (aortic type) with a unique intron site.Molecular and cellular biology · 1984Article
- Expression of the genes coding for the skeletal muscle and cardiac actions in the heart.Nucleic acids research · 1984Article
- Human actin genes are single copy for alpha-skeletal and alpha-cardiac actin but multicopy for beta- and gamma-cytoskeletal genes: 3' untranslated regions are isotype specific but are conserved in evolution.Molecular and cellular biology · 1983Article
- Organization and evolution of the actin gene family in sea urchins.Molecular and cellular biology · 1983Article
- Biphasic regulation by dibutyryl cyclic AMP of tubulin and actin mRNA levels in neuroblastoma cells.Proceedings of the National Academy of Sciences of the United States of America · 1983Article
- The nucleotide sequence of the rat cytoplasmic beta-actin gene.Nucleic acids research · 1983Article
- DNA sequence of two linked actin genes of sea urchin.Molecular and cellular biology · 1983Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
Southern blots of rat genomic DNA indicate the existence of at least 12 EcoRI DNA fragments containing actin gene sequences. By using specific probes and stringent conditions of hybridization, it was found that only one of these fragments contains sequences of the skeletal muscle alpha-actin gene. Recombinant bacteriophages originating from eight different actin genes were isolated from rat genomic DNA libraries. One of them, Act 15, contains the skeletal muscle actin gene. Another clone, Act I, contains a gene coding for a cytoplasmic actin, identified tentatively as the beta-actin gene. Both genes have a large intron very close to the 5' end of their transcribed region, followed by several small introns. DNA sequence analysis and comparison with the available data on actin genes in other organisms indicated an interesting relationship between the positions of introns and the evolutionary relatedness. Several intron sites are conserved from at least the echinoderms to the vertebrates; others appear to be present in some actin genes and not in others.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.