ArticleProceedings of the National Academy of Sciences of the United States of America1981
Polarity of some motility-related microtubules.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1981. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
What it found
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Who cites it
49 citing papers in PubMed, 133 citations in OpenAlex.
- JHY enables the transition from switchable to fixed ciliary waveforms in metazoan evolution.EMBO reports · 2026Article
- The Small Interactor of PKD2 protein promotes the assembly and ciliary entry of the Chlamydomonas PKD2-mastigoneme complexes.Journal of cell science · 2024Article
- Wdr47, Camsaps, and Katanin cooperate to generate ciliary central microtubules.Nature communications · 2021Article
- Tracheal motile cilia in mice require CAMSAP3 for the formation of central microtubule pair and coordinated beating.Molecular biology of the cell · 2021Article
- A lumenal interrupted helix in human sperm tail microtubules.Scientific reports · 2018Article
- Chirality of the cytoskeleton in the origins of cellular asymmetry.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Review
- Tubulin transport by IFT is upregulated during ciliary growth by a cilium-autonomous mechanism.The Journal of cell biology · 2015Article
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- Self-organized optical device driven by motor proteins.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Cryo-electron tomography reveals conserved features of doublet microtubules in flagella.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- PF15p is the chlamydomonas homologue of the Katanin p80 subunit and is required for assembly of flagellar central microtubules.Eukaryotic cell · 2004Article
- Uniform polarity microtubule assemblies imaged in native brain tissue by second-harmonic generation microscopy.Proceedings of the National Academy of Sciences of the United States of America · 2003Article
- Dynamic behavior of microtubules during dynein-dependent nuclear migrations of meiotic prophase in fission yeast.Molecular biology of the cell · 2001Article
- Conditional mutations in gamma-tubulin reveal its involvement in chromosome segregation and cytokinesis.Molecular biology of the cell · 2001Article
- Feedback interactions between cell-cell adherens junctions and cytoskeletal dynamics in newt lung epithelial cells.Molecular biology of the cell · 2000Article
- A cytoplasmic dynein heavy chain is required for oscillatory nuclear movement of meiotic prophase and efficient meiotic recombination in fission yeast.The Journal of cell biology · 1999Article
- Regulation of organelle movement in melanophores by protein kinase A (PKA), protein kinase C (PKC), and protein phosphatase 2A (PP2A).The Journal of cell biology · 1998Article
- Actomyosin-based retrograde flow of microtubules in the lamella of migrating epithelial cells influences microtubule dynamic instability and turnover and is associated with microtubule breakage and treadmilling.The Journal of cell biology · 1997Article
- Heterotrimeric kinesin-II is required for the assembly of motile 9+2 ciliary axonemes on sea urchin embryos.The Journal of cell biology · 1997Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have investigated the structural polarity of microtubules from several systems in which these fibers are thought to contribute to cell motility. By using a method for displaying microtubule polarity in the electron microscope, we find that both the A and B subfibers of Tetrahymena ciliary outer doublets and the inner pair of single microtubules are all oriented with their plus ends (i.e., their fast-growing ends) distal to the basal body. All of the microtubules in the axopodia of the heliozoan Actinosphaerium and all of the microtubules in the processes of melanophores from the angelfish Pterophyllum are likewise oriented with their plus ends distal to the cell centers. These results suggest that cellular systems for motility, and even those capable of bidirectional motility, can be constructed from microtubules of a single polarity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.