Evidence map›Paper›PMID 6750225›Full record

ReviewKlinische Wochenschrift1982

Macrophage functions in antimicrobial defense.

T Schaffner, H U Keller, M W Hess, H Cottier

Abstract readReview
PubMed Publisher
In one paragraph

Review in Klinische Wochenschrift, 1982. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

  1. Recent progress of macrophage vesicle-based drug delivery systems.Drug delivery and translational research · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

T Schaffner
H U Keller
M W Hess
H Cottier
University of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present short review article, we discuss some recent findings regarding the role of macrophages in antimicrobial defense. Problems that are briefly considered include the production of monocytes and its modification in infectious diseases; the role of circulating monocytes and "fixed" macrophages in the blood stream; emigration of monocytes from the vascular bed and their accumulation at sites of microbial attack; role of macrophages in immune responses; stimulation and activation of these cells including secretory functions; attachment to their surface and phagocytosis of microorganisms; microbicidal activities of macrophages; their role in granuloma formation; inherited and acquired deficiencies of macrophage functions. Emphasis is placed on currently unresolved problems.

Indexed as

AnimalsBacteriaCell MovementGranulomaGuinea PigsHumansInfectionsMacrophage ActivationMacrophagesMiceMonocytesPhagocytosis

Identifiers

PMID6750225
OpenAlexW2041094716

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.