Evidence map›Paper›PMID 6744661›Full record

ArticleClinical and experimental immunology1984

Surface proteins of the human eosinophil. II. Effects of Schistosoma mansoni larvae on eosinophil surface proteins.

K J Thorne, B A Richardson, A E Butterworth

Open access · greenAbstract read
In one paragraph

Article in Clinical and experimental immunology, 1984. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Eosinophils. Assays and interpretation.Clinical reviews in allergy · 1988
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

K J Thorne
B A Richardson
A E Butterworth

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Incubation of eosinophils with schistosoma of Schistosoma mansoni in vitro induces changes in the eosinophil membrane. Cell surface proteins were blocked with unlabelled iodide and then, after incubation with schistosomula, newly accessible proteins were detected by lactoperoxidase catalysed iodination with radioactive iodide. Normal turnover restores several proteins to the eosinophil surface, but the schistosomula specifically induced the appearance of a protein of mol. wt 18K. This protein has previously been detected when eosinophils interact with antibody coated agar layers. Soluble factors released by schistosomula induced the appearance of enhanced levels of 16 and 18K proteins. It has previously been shown that proteins involved in binding of eosinophils to IgG coated antigen coupled cellulose have mol. wts of 16K and 18K.

Indexed as

Antigen-Antibody ComplexChemotactic Factors, EosinophilEosinophilsHumansImmunoglobulin GMembrane ProteinsSchistosoma mansoniSolubilityAntigen-Antibody ComplexChemotactic Factors, EosinophilImmunoglobulin GMembrane Proteins

Identifiers

PMID6744661
PMCPMC1536008
OpenAlexW194314566

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.