ArticleJournal of clinical pathology1984
Selenium and vitamin E in relation to risk factors for coronary heart disease.
Article in Journal of clinical pathology, 1984. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 81 citations in OpenAlex.
- Comparative Analysis of Inflammatory and Heavy Metal Biomarkers in Exclusive E-Cigarette Users, Combustible Tobacco Users, and Non-Users Aged 18-30: A Cross-Sectional NHANES Analysis.Journal of xenobiotics · 2025Article
- Crystal structure of 1,1'-[selanediyl-bis(4,1-phenyl-ene)]bis-(2-chloro-ethan-1-one).Acta crystallographica. Section E, Crystallographic communications · 2015Article
- Association of smoking with serum and dietary levels of antioxidants in adults: NHANES III, 1988-1994.American journal of public health · 2001Article
- Mercury and selenium in workers previously exposed to mercury vapour at a chloralkali plant.British journal of industrial medicine · 1993Article
- Serum selenium and precursors of cardiovascular risk factors in adolescents.European journal of epidemiology · 1991Article
- Rapid and simple determination of selenium and other trace elements in very small blood samples by XRF.Biological trace element research · 1988Article
- Possible role of deficiency of selenium and vitamin E in atherosclerosis.Journal of clinical pathology · 1984Article
- Serum selenium in adult Czechoslovak (central Bohemia) population.Biological trace element researchArticle
- Serum selenium levels in Slovak population.Biological trace element researchArticle
- The distribution of selenium in human blood samples of Israeli population--comparison between normal and breast cancer cases.Biological trace element researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fasting blood samples taken from 116 apparently healthy men aged 30-50 years were assayed for selenium, glutathione peroxidase activity, vitamin E, cadmium, lead, glucose, lipids, and albumin. Blood pressure was measured in each subject, and details of height, weight, smoking habits, and alcohol consumption were recorded. Multivariate analysis of the data showed that the decrease in blood and serum concentrations of selenium and the increase in whole blood cadmium concentrations in the cigarette smokers was independent of alcohol consumption. There was no correlation between blood selenium concentrations or glutathione peroxidase activities and the risk factors for cardiovascular disease. Neither alcohol consumption nor smoking had an effect on the vitamin E concentrations. There was a strong association, however, between vitamin E and serum lipid concentrations, although the increase in triglyceride concentrations in the smokers was not matched by a comparable increase in vitamin E. The possible role of selenium in the aetiology of heart disease remains unresolved.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.