Evidence map›Paper›PMID 6690475›Full record

ArticleThe Journal of clinical investigation1984

Actin expression in smooth muscle cells of rat aortic intimal thickening, human atheromatous plaque, and cultured rat aortic media.

G Gabbiani, O Kocher, W S Bloom, J Vandekerckhove, K Weber

Abstract read
In one paragraph

Article in The Journal of clinical investigation, 1984. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Connexin mRNA distribution in adult mouse kidneys.Pflugers Archiv : European journal of physiology · 2021
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  5. Article
  6. Review
  7. Article
  8. Article
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  11. Article
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  14. Article
  15. Collagen represses canonical Notch signaling and binds to Notch ectodomain.The international journal of biochemistry & cell biology · 2013
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

G Gabbiani
O Kocher
W S Bloom
J Vandekerckhove
K Weber

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Actin of smooth muscle cells of rat and human aortic media shows a predominance of the alpha-isoform. In experimental rat aortic intimal thickening, in human atheromatous plaque, and in cultured aortic smooth muscle cells, there is a typical switch in actin expression with a predominance of the beta-form and a noticeable amount of gamma-form. This pattern of actin expression represents a new reliable protein-chemical marker of experimental and human atheromatous smooth muscle cells.

Indexed as

ActinsAdolescentAdultAgedAnimalsAorta, ThoracicArteriosclerosisChildFemaleHumansIsoelectric FocusingMaleMiddle AgedMuscle, Smooth, VascularPhenotypeRatsActins

Identifiers

PMID6690475
PMCPMC424985

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.