ArticleThe Journal of cell biology1984
ATP-induced gelation--contraction of microtubules assembled in vitro.
Article in The Journal of cell biology, 1984. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- From isolated structures to continuous networks: A categorization of cytoskeleton-based motile engineered biological microstructures.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2019Review
- α-Synuclein Fibrils Exhibit Gain of Toxic Function, Promoting Tau Aggregation and Inhibiting Microtubule Assembly.The Journal of biological chemistry · 2016Article
- Active contraction of microtubule networks.eLife · 2015Article
- The novel protein KBP regulates mitochondria localization by interaction with a kinesin-like protein.BMC cell biology · 2005Article
- Induction of multipolar mitoses in cultured cells: decay and restructuring of the mitotic apparatus and distribution of centrioles.Chromosoma · 1991Article
- The transport and assembly of the axonal cytoskeleton.The Journal of cell biology · 1989Review
- ATP-dependent formation and motility of aster-like structures with isolated calf brain microtubule proteins.Proceedings of the National Academy of Sciences of the United States of America · 1986Article
- Reorganization of microtubules in endosperm cells and cell fragments of the higher plant Haemanthus in vivo.The Journal of cell biology · 1986Article
- Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility.Cell · 1985Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
We report here an ATP-dependent formation and contraction, or syneresis, of a microtubule gel using microtubule proteins prepared from calf brains. Gel contraction is typically observable 15-30 min after ATP addition to microtubules assembled to steady state, and is complete after approximately 60 min, at which time the gel volume is reduced by as much as 75%. In contracted gels, microtubule bundles and aster-like structures are observable. Gelation-contraction requires only microtubule proteins present after purification by three cycles of assembly and disassembly.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.