ArticleInfection and immunity1983
Murine encephalitozoonosis model for studying the host-parasite relationship of a chronic infection.
Article in Infection and immunity, 1983. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 94 citations in OpenAlex.
- Encephalitozoonosis in Pet Rabbits: Epidemiology, Pathogenesis, Immunology and Consensus on Clinical Management.Animals : an open access journal from MDPI · 2026Review
- Immune Response to Microsporidia.Experientia supplementum (2012) · 2022Article
- Characterization of a Murine Model forMicroorganisms · 2020Article
- Characterization of humoral and cell-mediated immunity in rabbits orally infected with Encephalitozoon cuniculi.Veterinary research · 2020Article
- Cisplatin-induced ototoxicity in organotypic cochlear cultures occurs independent of gap junctional intercellular communication.Cell death & disease · 2020Article
- Innate and Adaptive Immune Responses Against Microsporidia Infection in Mammals.Frontiers in microbiology · 2020Review
- Microsporidia: Obligate Intracellular Pathogens Within the Fungal Kingdom.Microbiology spectrum · 2017Review
- Effector CD8 T cell immunity in microsporidial infection: a lone defense mechanism.Seminars in immunopathology · 2015Review
- First detection of an ignored parasite, Encephalitozoon cuniculi, in different animal hosts in Egypt.Parasitology research · 2015Article
- Pathology of Experimental Encephalitozoon cuniculi Infection in Immunocompetent and Immunosuppressed Mice in Iraq.Pathology research international · 2014Article
- Article
- Gastrointestinal cell mediated immunity and the microsporidia.PLoS pathogens · 2012Article
- Purified PTP1 protein induces antigen-specific protective immunity against Encephalitozoon cuniculi.Microbes and infection · 2010Article
- Encephalitozoonosis in rabbits.Parasitology research · 2010Review
- Aging mice exhibit a functional defect in mucosal dendritic cell response against an intracellular pathogen.Journal of immunology (Baltimore, Md. : 1950) · 2008Article
- The immunology of parasite infections in immunocompromised hosts.Parasite immunology · 2006Review
- Induction of a rapid and strong antigen-specific intraepithelial lymphocyte response during oral Encephalitozoon cuniculi infection.Journal of immunology (Baltimore, Md. : 1950) · 2004Article
- Immune response to Encephalitozoon cuniculi infection.Microbes and infection · 2001Review
- Molecular techniques for detection, species differentiation, and phylogenetic analysis of microsporidia.Clinical microbiology reviews · 1999Review
- Role of gamma interferon in cellular immune response against murine Encephalitozoon cuniculi infection.Infection and immunity · 1999Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Encephalitozoon cuniculi caused chronic nonlethal infections in euthymic BALB/cAnN mice, whereas athymic BALB/cAnN-nu mice died from infection. Specific, anamnestic, transferable, and acquired responses against E. cuniculi were expressed by infected euthymic mice. Resistance to lethal disease appears to be T-cell dependent. Immune serum failed to protect infected athymic mice, whereas the transfer of T-enriched spleen cells from E. cuniculi-sensitized euthymic donors prevented lethal E. cuniculi infections in athymic mice. These findings indicate that murine encephalitozoonosis may be an excellent system for studies of a chronic infection in an immunologically well-characterized host.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.