ArticleEuropean journal of clinical microbiology1984
Wound infection rates after intraincisional plus systemic antibiotic prophylaxis in an animal model.
Article in European journal of clinical microbiology, 1984. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 3 citations in OpenAlex.
- A randomized trial of one versus three doses of Augmentin as wound prophylaxis in at-risk abdominal surgery.Postgraduate medical journal · 1992Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The effect of intraincisional application of antibiotics in addition to systemic antibiotic prophylaxis was evaluated in a randomized blind study using a guinea pig model of surgical wound infection. Wounds were contaminated with 10(7) Escherichia coli plus 10(8) Bacteroides fragilis. Wound infection was defined as accumulation of pus draining spontaneously or after opening the wound. Systemic antibiotic prophylaxis with gentamicin plus clindamycin significantly reduced the wound sepsis rate from 83% in the control group to 20% in the treated group (p less than 0.001). Intraincisional application of antibiotics in addition to systemic prophylaxis did not further reduce the rate of wound sepsis (p greater than 0.8).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.