ArticleProceedings of the National Academy of Sciences of the United States of America1984
Lysosomes are associated with microtubules and not with intermediate filaments in cultured fibroblasts.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1984. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Article
- Disruption of microtubule function in cultured human cells by a cytotoxic ruthenium(ii) polypyridyl complex.Chemical science · 2019Article
- Tau-Induced Pathology in Epilepsy and Dementia: Notions from Patients and Animal Models.International journal of molecular sciences · 2018Review
- Dynamic fingerprinting of sub-cellular nanostructures by image mean square displacement analysis.Scientific reports · 2017Article
- GOLPH3 drives cell migration by promoting Golgi reorientation and directional trafficking to the leading edge.Molecular biology of the cell · 2016Article
- Spatial and Structural Metrics for Living Cells Inspired by Statistical Mechanics.Scientific reports · 2016Article
- Increased spinal cord Na⁺-K⁺-2Cl⁻ cotransporter-1 (NKCC1) activity contributes to impairment of synaptic inhibition in paclitaxel-induced neuropathic pain.The Journal of biological chemistry · 2014Article
- Ablation of vimentin results in defective steroidogenesis.Endocrinology · 2012Article
- Effects of paclitaxel on EGFR endocytic trafficking revealed using quantum dot tracking in single cells.PloS one · 2012Article
- Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones.Nutrition & metabolism · 2010Article
- Vimentin is a functional partner of hormone sensitive lipase and facilitates lipolysis.Journal of proteome research · 2010Article
- Stable, detyrosinated microtubules function to localize vimentin intermediate filaments in fibroblasts.The Journal of cell biology · 1995Article
- Release of lysosomal protease from retinal pigment epithelium and fibroblasts during mechanical stresses.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 1995Article
- Cellular expression of the beige mouse mutation and its correction in hybrids with control human fibroblasts.In vitro cellular & developmental biology. Animal · 1993Article
- Indirect immunofluorescence modified to display two antigens with one light filter.The Histochemical journal · 1993Article
- Colchicine myoneuropathy and renal dysfunction.Annals of the rheumatic diseases · 1992Article
- Cytoplasmic dynein participates in the centrosomal localization of the Golgi complex.The Journal of cell biology · 1992Article
- Parasitophorous vacuoles of Leishmania amazonensis-infected macrophages maintain an acidic pH.Infection and immunity · 1990Article
- Hypothesis: microtubules, a key to Alzheimer disease.Proceedings of the National Academy of Sciences of the United States of America · 1989Article
- Changes in lysosome shape and distribution correlated with changes in cytoplasmic pH.The Journal of cell biology · 1989Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Double immunofluorescent labeling experiments for lysosomes and either microtubules or vimentin intermediate filaments in cultured well-spread fibroblasts show a remarkable degree of superposition of the lysosomes and the microtubules. Under two different sets of conditions where the microtubules and intermediate filaments are well segregated from one another, the lysosomes remain codistributed with the microtubules. It is suggested that this specific association of lysosomes with microtubules reflects some type(s) of linkage(s) between them and that such linkages may play an important role in the location and intracellular transport of lysosomes inside cells.
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