ArticleThe American journal of pathology1983
The immunochemical characterization of mesangial IgA deposits.
Article in The American journal of pathology, 1983. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 98 citations in OpenAlex.
- The involvement of Anaeroplasma, caproic acid, and interleukins through the brain-gut axis may contribute to IgAV with neurological involvement.Pediatric research · 2026Article
- Secondary IgA nephropathy.Kidney international · 2018Review
- Kidneys in chronic liver diseases.World journal of gastroenterology · 2012Review
- Pathogenesis of Henoch-Schönlein purpura nephritis.Pediatric nephrology (Berlin, Germany) · 2010Review
- Pathogenetic significance of aberrant glycosylation of IgA1 in IgA nephropathy.Clinical and experimental nephrology · 2008Review
- Selective expansion of T cell receptor (TCR) V beta 6 in tonsillar and peripheral blood T cells and its induction by in vitro stimulation with Haemophilus parainfluenzae in patients with IgA nephropathy.Clinical and experimental immunology · 2008Article
- Association of liver cirrhosis related IgA nephropathy with portal hypertension.World journal of gastroenterology · 2007Article
- Increase of both circulating Th1 and Th2 T lymphocyte subsets in IgA nephropathy.Clinical and experimental immunology · 1994Article
- IgA nephropathy in children and adults.Springer seminars in immunopathology · 1994Review
- Immunopathogenesis of experimental IgA nephropathy.Springer seminars in immunopathology · 1994Review
- Secretory IgA are elevated in both saliva and serum of patients with various types of primary glomerulonephritis.Clinical and experimental immunology · 1992Article
- Increased and prolonged production of specific polymeric IgA after systemic immunization with tetanus toxoid in IgA nephropathy.Clinical and experimental immunology · 1992Article
- Light-chain ratio of serum IgA1 in IgA nephropathy.Journal of clinical immunology · 1991Article
- Humoral immune response to influenza vaccination in patients with primary immunoglobulin A nephropathy. An analysis of isotype distribution and size of the influenza-specific antibodies.The Journal of clinical investigation · 1989Article
- Increased serum levels of IgA1-IgG immune complexes and anti-F(ab')2 antibodies in patients with primary IgA nephropathy.Clinical and experimental immunology · 1989Article
- Quantitation of human serum polymeric IgA, IgA1 and IgA2 immunoglobulin by enzyme immunoassay.Clinical and experimental immunology · 1988Article
- Predominance of IgA deposits in glomeruli of Schistosoma mansoni infected mice.Clinical and experimental immunology · 1988Article
- Glomerular immune deposits in experimental IgA nephropathy. A continuum of circulating and in situ formed immune complexes.The American journal of pathology · 1988Article
- IgA-associated renal diseases: antibodies to environmental antigens in sera and deposition of immunoglobulins and antigens in glomeruli.Journal of clinical immunology · 1986Article
- Contribution of secretory IgA, polymeric IgA and IgA/secretory component-containing circulating immune complexes to the serum hyper-IgA in diabetes mellitus.Diabetologia · 1984Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mesangial deposits of IgA are found in IgA nephropathy, Schönlein-Henoch purpura (SHP) and in some patients with alcoholic cirrhosis and systemic lupus erythematosus (SLE). In this study the authors characterized the mesangial IgA deposits in patients with the above diseases using antiserums or monoclonal antibodies to A1, A2, J-chain and secretory component (SC), and examined SC binding in vitro. SC was not present, J-chain was ubiquitous, and A2 was found (with the use of monoclonal antibodies) rarely but with equal frequency in all groups. The SC binding capacity of the deposits differed between the groups and was found in 13 of 16 patients with alcoholic liver disease, 3 of 4 with SLE, 1 of 10 with primary IgA nephropathy, and none of 6 with SHP.
Indexed as
Identifiers
6359892PMC1916361W1638267296What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.