ReviewThe Histochemical journal1983
Antibodies to intermediate filament proteins in the immunohistochemical identification of human tumours: an overview.
Review in The Histochemical journal, 1983. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
66 citing papers in PubMed, 325 citations in OpenAlex.
- The Expression Pattern of Epidermal Differentiation Marker Keratin 10 in the Normal Human Breast and Breast Cancer Cells.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2020Article
- Morphological changes of telocytes in camel efferent ductules in response to seasonal variations during the reproductive cycle.Scientific reports · 2019Article
- Smoothelin, a novel cytoskeletal protein specific for smooth muscle cells.The Journal of cell biology · 1996Article
- Human multidrug resistance 3-P-glycoprotein expression in transgenic mice induces lens membrane alterations leading to cataract.The Journal of cell biology · 1996Article
- Differential processes of vascular smooth muscle cell differentiation within elastic and muscular arteries of rats and rabbits: an immunofluorescence study of desmin and vimentin distribution.The Histochemical journal · 1996Article
- Fat-storing cells and myofibroblasts are involved in the initial phase of carbon tetrachloride-induced hepatic fibrosis in BN/BiRij rats.International journal of experimental pathology · 1994Article
- S-phase determination of immunoselected cytokeratin-containing breast cancer cells improves the prediction of recurrence.Breast cancer research and treatment · 1994Article
- Repeated tape stripping of normal skin: a histological assessment and comparison with events seen in psoriasis.Archives of dermatological research · 1994Article
- Detection of keratin subtypes in routinely processed cervical tissue: implications for tumour classification and the study of cervix cancer aetiology.Virchows Archiv : an international journal of pathology · 1994Article
- Article
- Changes in expression of differentiation markers between normal ovarian cells and derived tumors.The American journal of pathology · 1993Article
- Mycobacterial 65,000 MW heat-shock protein shares a carboxy-terminal epitope with human epidermal cytokeratin 1/2.Immunology · 1992Article
- Differentiation of human skeletal muscle cells in culture: maturation as indicated by titin and desmin striation.Cell and tissue research · 1992Article
- Intermediate filaments as differentiation markers of normal pancreas and pancreas cancer.The American journal of pathology · 1992Article
- Establishment and characterization of five new human renal tumor xenografts.The American journal of pathology · 1992Article
- Keratin profiles in normal/hyperplastic prostates and prostate carcinoma.Virchows Archiv. A, Pathological anatomy and histopathology · 1992Article
- Antiperinuclear factor, a marker autoantibody for rheumatoid arthritis: colocalisation of the perinuclear factor and profilaggrin.Annals of the rheumatic diseases · 1991Article
- Differential immunohistochemical detection of cytokeratins and vimentin in the surgically removed human endolymphatic duct and sac.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 1991Article
- Expression of cytokeratin polypeptides during development of the rat inner ear.Histochemistry · 1991Article
- Cytokeratin expression in the epithelia of the adult human cochlea.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 1991Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intermediate-sized filament proteins (IFP) are tissue specific in that antibodies to keratin, vimentin, desmin, glial fibrillary acidic protein (GFAP) and the neurofilament proteins can distinguish between cells of epithelial and mesenchymal origin as well as of myogenic and neural origin respectively. Malignant cells retain their tissue-specific IFP, which makes it possible to use these antibodies in tumour diagnosis. Carcinomas are exclusively detected by antibodies to keratin. Monoclonal antibodies to keratin have allowed the differentiation between subgroups of epithelial tumours until now between adenocarcinomas and squamous cell carcinomas. Lymphomas, melanomas and several soft tissue tumours are distinctly recognized by antibodies to vimentin. On the other hand, rhabdomyosarcomas and leiomyosarcomas are positive for desmin, while astrocytomas give a strong reaction with GFAP antibodies. Thus, antibodies to IFP are useful tools for differential diagnosis in surgical pathology.
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