Evidence map›Paper›PMID 6345591›Full record

ReviewJournal of clinical pathology1983

Granulomatous inflammation--a review.

G T Williams, W J Williams

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical pathology, 1983. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

115 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Granulomatous Cutaneous Drug Eruptions: A Systematic Review.American journal of clinical dermatology · 2021
    Pooled it
  2. Article
  3. A Case of Bilateral Cheek Foreign Body Granulomas Caused by Absorbable Filler.Journal of plastic and reconstructive surgery · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
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  11. Review
  12. Article
  13. Article
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  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. The dense-core plaques of Alzheimer's disease are granulomas.The Journal of experimental medicine · 2022
    Article

55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

G T Williams
W J Williams

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The granulomatous inflammatory response is a special type of chronic inflammation characterised by often focal collections of macrophages, epithelioid cells and multinucleated giant cells. In this review the characteristics of these cells of the mononuclear phagocyte series are considered, with particular reference to the properties of epithelioid cells and the formation of multinucleated giant cells. The initiation and development of granulomatous inflammation is discussed, stressing the importance of persistence of the inciting agent and the complex role of the immune system, not only in the perpetuation of the granulomatous response but also in the development of necrosis and fibrosis.

Indexed as

GranulomaGranuloma, Giant CellHumansMacrophage ActivationMacrophagesMonocytesNecrosisPhagocytesPhagocytosisPinocytosis

Identifiers

PMID6345591
PMCPMC498378

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.