ArticleCell and tissue research1983
Serotonin axons of the ependyma and circumventricular organs in the forebrain of the guinea pig. An immunohistochemical study.
Article in Cell and tissue research, 1983. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 51 citations in OpenAlex.
- History of research concerning the ependyma: a view from inside the human brain.Frontiers in cellular neuroscience · 2023Review
- Implication of 5-HT in the Dysregulation of Chloride Homeostasis in Prenatal Spinal Motoneurons from the G93A Mouse Model of Amyotrophic Lateral Sclerosis.International journal of molecular sciences · 2020Article
- The neural milieu of the developing choroid plexus: neural stem cells, neurons and innervation.Frontiers in neuroscience · 2015Article
- Ontogenic changes of the spinal GABAergic cell population are controlled by the serotonin (5-HT) system: implication of 5-HT1 receptor family.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2005Article
- Descending 5-hydroxytryptamine raphe inputs repress the expression of serotonergic neurons and slow the maturation of inhibitory systems in mouse embryonic spinal cord.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2002Article
- Central control of blood pressure by nitrergic mechanisms in organum vasculosum laminae terminalis of rat brain.British journal of pharmacology · 1999Article
- Protein-gold complexes as neuronal markers for long-term tracing studies.Histochemistry · 1989Article
- Immunohistochemical demonstration of serotonergic and peptidergic nerve fibers in the subcommissural organ of the dog.Cell and tissue research · 1987Article
- Characteristic pattern of monoaminergic nerve fibers in the pineal organ of the monkey, Macaca fuscata.Cell and tissue research · 1986Article
- Anti-5-hydroxytryptamine antibodies: studies on their cross-reactivity in vitro and their immunohistochemical specificity.Experimental brain research · 1986Article
- Serotonin distribution in the circumventricular organs of the rat. An immunohistochemical study.Anatomy and embryology · 1983Article
- distribution of monoamine-containing nerve fibers in the pineal organ of untreated and sympathectomized dogs. Fluorescence- and immunohistochemical studies.Cell and tissue research · 1983Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The distribution of supraependymal nerve fibers (SEF) containing serotonin (5-HT) was investigated immunohistochemically in the forebrain of the guinea pig. The highest densities of immunoreactive axons were found in the pars centralis and the inferior horn of the lateral ventricle and also in the superior part of the third ventricle. Because of the special development of the choroid plexus in these ventricular regions, it is suggested that 5-HT SEF might be involved in the regulation of the composition of the cerebrospinal fluid. The ependyma lining the circumventricular organs located in the forebrain, was not observed to receive a significant 5-HT-SEF innervation. In the pituitary gland, a loose but constant network of 5-HT axons, resembling those which course in the anterobasal hypothalamus, arcuate nucleus and internal layer of the median eminence, was observed in the neural lobe. In the epiphysis, immunoreactive 5-HT was detected in all pinealocytes (the entire cell was filled with reaction product) and in fibers running between them.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.