ArticleMolecular and cellular biology1984
Drosophila melanogaster has only one myosin alkali light-chain gene which encodes a protein with considerable amino acid sequence homology to chicken myosin alkali light chains.
Article in Molecular and cellular biology, 1984. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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30 citing papers in PubMed, 66 citations in OpenAlex.
- Comparative transcriptome analyses of the Drosophila pupal eye.G3 (Bethesda, Md.) · 2021Article
- Alternative N-terminal regions ofThe Journal of biological chemistry · 2020Article
- Planarian myosin essential light chain is involved in the formation of brain lateral branches during regeneration.Molecular genetics and genomics : MGG · 2015Article
- Transcriptional regulation of the Drosophila melanogaster muscle myosin heavy-chain gene.Gene expression patterns : GEP · 2007Article
- Isolation and kinetic characterisation of myosin and myosin S1 from the Drosophila indirect flight muscles.Journal of muscle research and cell motility · 2003Article
- Alterations in flight muscle ultrastructure and function in Drosophila tropomyosin mutants.The Journal of cell biology · 1996Article
- Distinct gene expression patterns in skeletal and cardiac muscle are dependent on common regulatory sequences in the MLC1/3 locus.Molecular and cellular biology · 1996Article
- Actomyosin kinetics and in vitro motility of wild-type Drosophila actin and the effects of two mutations in the Act88F gene.Biophysical journal · 1995Article
- Article
- Drosophila melanogaster genes encoding three troponin-C isoforms and a calmodulin-related protein.Biochemical genetics · 1994Article
- Myosin light chain-2 mutation affects flight, wing beat frequency, and indirect flight muscle contraction kinetics in Drosophila.The Journal of cell biology · 1992Article
- Muscle abnormalities in Drosophila melanogaster heldup mutants are caused by missing or aberrant troponin-I isoforms.The Journal of cell biology · 1991Article
- Fish myosin alkali light chains originate from two different genes.Journal of muscle research and cell motility · 1991Article
- Myosin light chains and troponin C: structural and evolutionary relationships revealed by amino acid sequence comparisons.Journal of muscle research and cell motility · 1991Review
- Evolution of EF-hand calcium-modulated proteins. I. Relationships based on amino acid sequences.Journal of molecular evolution · 1990Article
- Structure and expression of a muscle specific gene which is adjacent to the Drosophila myosin heavy-chain gene and can encode a cytochrome b related protein.Nucleic acids research · 1989Article
- Article
- Characterization of the gene for mp20: a Drosophila muscle protein that is not found in asynchronous oscillatory flight muscle.The Journal of cell biology · 1989Article
- Molecular and ultrastructural defects in a Drosophila myosin heavy chain mutant: differential effects on muscle function produced by similar thick filament abnormalities.The Journal of cell biology · 1988Article
- Regulatory myosin light-chain genes of Caenorhabditis elegans.Molecular and cellular biology · 1988Article
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4 authors at 1 institution in 1 country.
Funding
Abstract
A chimeric lambda DNA molecule containing the myosin alkali light-chain gene of Drosophila melanogaster was isolated. The encoded amino acid sequence was determined from the nucleic acid sequence of a cDNA homologous to the genomic clone. The identity of the encoded protein was established by two criteria: (i) sequence homology with the chicken alkali light-chain proteins and (ii) comparison of the two-dimensional gel electrophoretic pattern of the peptides synthesized by in vitro translation of hybrid-selected RNA to that of myosin alkali light-chain peptides extracted from Drosophila myofibrils. There is only one myosin alkali light-chain in D. melanogaster; its chromosomal location is region 98B . This gene is abundantly expressed during the development of larval as well as adult muscles. The Drosophila protein appears to contain one putative divalent cation-binding domain (an EF hand) as compared with the three EF hands present in chicken alkali light chains.
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