ArticleProceedings of the National Academy of Sciences of the United States of America1984
Evidence for parallel actions of a molluscan neuropeptide and serotonin in mediating arousal in Aplysia.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1984. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 132 citations in OpenAlex.
- The Distribution and Possible Roles of Small Cardioactive Peptide in the NudibranchIntegrative organismal biology (Oxford, England) · 2020Article
- Multifaceted Expression of Peptidergic Modulation in the Feeding System of Aplysia.ACS chemical neuroscience · 2018Review
- Serotonin-immunoreactive neural system and contractile system in the hydroid Cladonema (Cnidaria, Hydrozoa).Invertebrate neuroscience : IN · 2013Article
- Neuronal control of pedal sole cilia in the pond snail Lymnaea stagnalis appressa.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2013Article
- Repetition priming of motoneuronal activity in a small motor network: intercellular and intracellular signaling.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
- Composite modulatory feedforward loop contributes to the establishment of a network state.Journal of neurophysiology · 2010Article
- Evolutionary conservation of the signaling proteins upstream of cyclic AMP-dependent kinase and protein kinase C in gastropod mollusks.Brain, behavior and evolution · 2009Review
- Regulation of behavioral and synaptic plasticity by serotonin release within local modulatory fields in the CNS of Aplysia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2006Article
- Variability of motor neuron spike timing maintains and shapes contractions of the accessory radula closer muscle of Aplysia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2006Article
- Temperature compensation of neuromuscular modulation in aplysia.Journal of neurophysiology · 2005Article
- Temporal pattern dependence of neuronal peptide transmitter release: models and experiments.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2000Article
- Serotonin and the small cardioactive peptides differentially modulate two motor neurons that innervate the same muscle fibers in Aplysia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1997Article
- Release of peptide cotransmitters in Aplysia: regulation and functional implications.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1996Article
- Functional organization of cotransmission systems: lessons from small nervous systems.Invertebrate neuroscience : IN · 1995Review
- cAMP-dependent phosphorylation of Aplysia twitchin may mediate modulation of muscle contractions by neuropeptide cotransmitters.Proceedings of the National Academy of Sciences of the United States of America · 1994Article
- Peptidergic co-transmission in Aplysia: functional implications for rhythmic behaviors.Experientia · 1992Review
- Peptidergic motoneurons in the buccal ganglia of Aplysia californica: immunocytochemical, morphological, and physiological characterizations.Journal of comparative physiology. A, Sensory, neural, and behavioral physiology · 1991Article
- Protein synthesis during acquisition of long-term facilitation is needed for the persistent loss of regulatory subunits of the Aplysia cAMP-dependent protein kinase.Proceedings of the National Academy of Sciences of the United States of America · 1990Article
- Release of peptide cotransmitters from a cholinergic motor neuron under physiological conditions.Proceedings of the National Academy of Sciences of the United States of America · 1990Article
- Frequency-dependent release of peptide cotransmitters from identified cholinergic motor neurons in Aplysia.Proceedings of the National Academy of Sciences of the United States of America · 1989Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The neuropeptide designated SCPB (small cardioactive peptide B), the sequence of which has recently been determined, was found in the accessory radula closer muscle, a muscle involved in biting movements. The ganglia and nerves that innervate the accessory radula closer muscle also contain SCPB. At nanomolar concentrations, it enhances the contractions of the muscle. The effect of SCPB on the muscle resembles the effect of an identified serotonergic neuron that previously was shown to mediate behavioral effects that reflect a food arousal state in Aplysia. Like serotonin, SCPB enhances contractions by a postsynaptic action, which appears to involve an increase in cAMP levels in the muscle. Our findings suggest that parallel peptidergic and serotonergic pathways may mediate similar aspects of arousal in Aplysia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.