Evidence map›Paper›PMID 6325350›Full record

ArticleInfection and immunity1984

Toxic effect of the peroxidase-hydrogen peroxide-halide antimicrobial system on Mycobacterium leprae.

S J Klebanoff, C C Shepard

Abstract readComparative Study
In one paragraph

Article in Infection and immunity, 1984. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

S J Klebanoff
C C Shepard

Funding

ANTIMICROBIAL EFFECT OF PEROXIDASE - ROLE IN LEUKOCYTESR01AI007763 · NIAID · UNIVERSITY OF WASHINGTON · PI KLEBANOFF, SEYMOUR J · 1985 to 1987
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ANTIMICROBIAL EFFECT OF PEROXIDASE--ROLE IN LEUKOCYTESR37AI007763 · NIAID · UNIVERSITY OF WASHINGTON · PI KLEBANOFF, SEYMOUR J · 1988 to 1999
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NIAID NIH HHS AI-07763
6 · The paper itself

Abstract

Mycobacterium leprae are killed by myeloperoxidase (or eosinophil peroxidase), H2O2, and a halide, thus suggesting a mechanism for their destruction by peroxidase-containing phagocytes.

Indexed as

Anti-Bacterial AgentsAnimalsBromidesChloridesDogsEosinophil PeroxidaseEosinophilsHorsesHydrogen PeroxideIodidesMycobacterium lepraePeroxidasePeroxidasesAnti-Bacterial AgentsBromidesChloridesEosinophil PeroxidaseHydrogen PeroxideIodidesPeroxidasePeroxidases

Identifiers

PMID6325350
PMCPMC263559

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.