Evidence map›Paper›PMID 6306057›Full record

ArticleJournal of clinical pathology1983

Immune complex nephritis in alcoholic cirrhosis: detection of Mallory body antigen in complexes by means of monoclonal antibodies to Mallory bodies.

J Burns, A J D'Ardenne, J A Morton, J O McGee

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical pathology, 1983. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 17 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

J Burns
A J D'Ardenne
J A Morton
J O McGee
John Radcliffe Hospital · GBUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A Mallory body (alcoholic hyaline) antigen (JMB2) which is also present in intermediate filaments of epithelial origin was demonstrated immunohistochemically in renal glomeruli of three out of eleven patients with alcoholic liver damage. In two of these patients, both of whom had alcoholic cirrhosis with Mallory bodies, it was associated with mesangial deposits of IgA and C3. JMB2 was not found in glomeruli of normal controls, nor in a series of cases of glomerulonephritis in non-alcoholic patients. It is concluded that JMB2 is present in immune complexes in renal glomeruli of patients with renal disease consequent on alcoholic liver disease.

Indexed as

Antibodies, MonoclonalAntigen-Antibody ComplexAntigensGlomerulonephritisHumansImmune Complex DiseasesImmunoglobulin AInclusion BodiesKidney GlomerulusLiverLiver Cirrhosis, AlcoholicProteinsAntibodies, MonoclonalAntigen-Antibody ComplexAntigensImmunoglobulin AMallory body protein, humanProteins

Identifiers

PMID6306057
PMCPMC498382
OpenAlexW2044772148

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.