ArticleMolecular and cellular biology1983
DNA sequence of two linked actin genes of sea urchin.
Article in Molecular and cellular biology, 1983. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 38 citations in OpenAlex.
- Evolution of actin gene families of sea urchins.Journal of molecular evolution · 1994Article
- Insect muscle actins differ distinctly from invertebrate and vertebrate cytoplasmic actins.Journal of molecular evolution · 1992Article
- Molecular phylogenetic analysis of actin genic regions from Achlya bisexualis (Oomycota) and Costaria costata (Chromophyta).Journal of molecular evolution · 1991Article
- Structure, chromosome location, and expression of the human smooth muscle (enteric type) gamma-actin gene: evolution of six human actin genes.Molecular and cellular biology · 1991Article
- Characterization of the rice (Oryza sativa) actin gene family.Plant molecular biology · 1990Article
- Identification and developmental expression of a smooth-muscle gamma-actin in postmeiotic male germ cells of mice.Molecular and cellular biology · 1989Article
- The 5' splice site: phylogenetic evolution and variable geometry of association with U1RNA.Nucleic acids research · 1989Article
- Cytoskeletal actin gene families of Xenopus borealis and Xenopus laevis.Journal of molecular evolution · 1988Article
- The sequence of a sea urchin muscle actin gene suggests a gene conversion with a cytoskeletal actin gene.Journal of molecular evolution · 1987Article
- The molecular evolution of actin.Genetics · 1986Article
- The complete sequence of the mouse skeletal alpha-actin gene reveals several conserved and inverted repeat sequences outside of the protein-coding region.Molecular and cellular biology · 1986Article
- Evolution of two actin genes in the sea urchin Strongylocentrotus franciscanus.Journal of molecular evolution · 1985Article
- Intron splicing: a conserved internal signal in introns of animal pre-mRNAs.Proceedings of the National Academy of Sciences of the United States of America · 1984Article
- Cytochrome oxidase subunit II gene of rice has an insertion sequence within the intron.Nucleic acids research · 1984Article
- Organization and evolution of the actin gene family in sea urchins.Molecular and cellular biology · 1983Article
- DNA sequence analysis and structural relationships among the cytoskeletal actin genes of the sea urchin Strongylocentrotus purpuratus.Journal of molecular evolutionArticle
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3 authors at 1 institution in 1 country.
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Abstract
DNA sequences have been determined for two actin genes which are closely linked in the genome of the sea urchin Strongylocentrotus purpuratus. The two genes have the same 5'-3' orientation; they were apparently formed originally by tandem gene duplication. The amino acids encoded by the two genes closely resemble those of cytoplasmic actins of mammals and slime molds and differ somewhat from those of mammalian muscle actin. Actin gene 1 had been tentatively identified earlier as the gene for an embryonic cytoplasmic actin by the homology of the 3' noncoding region with that of the cDNA of an embryonic actin mRNA from S. purpuratus. The DNA sequence of gene 1 shows presumptive signals for the initiation and termination of transcription which would govern the formation of a mature mRNA of 1.9 kilobases. Both actin genes 1 and 2 have introns in their coding regions at codons 121/122 and 204. These positions for actin introns have been reported so far only in the rat, not in lower organisms. The divergence of the sequences of these coding-region introns in the two actin genes is 66%, suggesting that the genes diverged about 90 million years ago. By contrast to the introns, the coding regions have been highly conserved; the amino acids of the two genes differ by only 1.3%, and the silent sites of the codons differ by only 12%.
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