Evidence map›Paper›PMID 6297224›Full record

ArticleActa neuropathologica1982

Globoid cell leukodystrophy: specialized contact of globoid cell with astrocyte in the brain of twitcher mouse.

H Takahashi, K Suzuki

Abstract read
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In one paragraph

Article in Acta neuropathologica, 1982. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

H Takahashi
K Suzuki

Funding

Support for MRRC - Biometry CoreP30HD001799 · NICHD · YESHIVA UNIVERSITY · PI FABER, DONALD S · 1985 to 2005
$6.5M
RETRIEVAL AND CLUSTERING IN DEVELOPMENT OF LEARNINGP01NS003356 · NINDS · YESHIVA UNIVERSITY · PI RAPIN, ISABELLE · 1985 to 1985
–
NICHD NIH HHS HD-01799NINDS NIH HHS NS-03356NINDS NIH HHS NS-10803
6 · The paper itself

Abstract

Subplasmalemmal linear densities (Yajima et al. 1977 a) were the membrane specializations observed in globoid cells in globoid cell leukodystrophy (GLD) and in the cells of the mononuclear phagocytic system (Kawanami et al. 1980). In the spinal cord of the twitcher mouse, an authentic murine model of GLD, somewhat similar membrane specializations were noted in astrocytes, and on some occasions, a spot desmosome-like cellular contact was observed between globoid cells, which were likely to be mesodermal in origin, and astrocytes, which are of ectodermal origin. Possible significance of such apparent cellular contact is discussed briefly.

Indexed as

AnimalsAstrocytesBrainCell CommunicationCytoskeletonInclusion BodiesIntercellular JunctionsLeukodystrophy, Globoid CellMiceMice, Neurologic MutantsSpinal Cord

Identifiers

PMID6297224

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.