ArticleInfection and immunity1982
Adhesion of Entamoeba histolytica trophozoites to human erythrocytes.
Article in Infection and immunity, 1982. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 21 citations in OpenAlex.
- Influence of Micropatterned Grill Lines onFrontiers in cellular and infection microbiology · 2018Article
- Feline Tritrichomonas foetus adhere to intestinal epithelium by receptor-ligand-dependent mechanisms.Veterinary parasitology · 2013Article
- Localisation to lipid rafts correlates with increased function of the Gal/GalNAc lectin in the human protozoan parasite, Entamoeba histolytica.International journal for parasitology · 2011Article
- Inhibitory activity of saccharomyces yeasts on the adhesion of Entamoeba histolytica trophozoites to human erythrocytes in vitro.Parasitology research · 1994Article
- Roles of target cell membrane carbohydrate and lipid in Entamoeba histolytica interaction with mammalian cells.Infection and immunity · 1990Article
- Specificity of glycosphingolipid recognition by Entamoeba histolytica trophozoites.Infection and immunity · 1990Article
- Inhibition of the adhesion of Entamoeba histolytica trophozoites to human erythrocytes by carbohydrates.Parasitology research · 1987Article
- Rapid polymerization of Entamoeba histolytica actin induced by interaction with target cells.The Journal of experimental medicine · 1985Article
- Adherence of Entamoeba histolytica trophozoites to rat and human colonic mucosa.Infection and immunity · 1985Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To understand the mechanism of Entamoeba histolytica adhesion, we characterized the binding of trophozoites to human erythrocytes (RBC) in suspension by measuring the kinetics of amoeba-RBC complex formation. Adhesion was very efficient, since most of the amoebae were complexed with RBC after only 5 min at 37 degrees C in mixtures containing 10(4) amoebae and 10(6) RBC per ml; the adhesion rate depended on amoeba and RBC concentrations, but not on the A, B, and O human blood groups, and was maximal at 37 degrees C and pH 7.3 in the presence of 4 mM Ca2+ and 1 mM Mg2+. Adhesion was prevented if trophozoites were fixed with glutaraldehyde, but only decreased slightly if RBC were previously fixed; it decreased in the absence of glucose and was inhibited as a function of the concentration of cytochalasin B and of the metabolic inhibitors bathophenanthroline and 8-hydroxyquinoline. From these results we conclude that E. histolytica adhesion is an active process that depends on the amoebal cytoskeleton and metabolic energy and on the mobility of both amoebal and RBC surface ligands.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.