ArticleProceedings of the National Academy of Sciences of the United States of America1983
Functional changes of intermediate filaments in fibroblastic cells revealed by a monoclonal antibody.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1983. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Construction and Characterization of Immortalized Skin Fibroblasts from Milu Deer.Animals : an open access journal from MDPI · 2025Article
- Myocardial composition and contractile function of right atrial trabeculae from type 2 diabetic and nondiabetic male patients.Physiological reports · 2025Article
- Fibroblasts in immune responses, inflammatory diseases and therapeutic implications.Nature reviews. Rheumatology · 2025Review
- Fibroblasts at the curtain call: from ensemble to principal dancers in immunometabolism and inflammaging.Journal of applied oral science : revista FOB · 2023Review
- Identification, discrimination and heterogeneity of fibroblasts.Nature communications · 2022Review
- Chitosan degradation products promote healing of burn wounds of rat skin.Frontiers in bioengineering and biotechnology · 2022Article
- Quantitative evaluation of vimentin expression in tumour stroma of colorectal cancer.British journal of cancer · 2007Article
- Expression of vimentin by rabbit corneal epithelial cells during wound repair.Cell and tissue research · 1992Article
- Synthesis and secretion of alpha 2-macroglobulin by human glioma established cell lines.Experimental brain research · 1992Article
- Differentiation patterns in two- and three-dimensional culture systems of human squamous carcinoma cell lines.The American journal of pathology · 1990Article
- The monoclonal antibody 22/18 recognizes a conformational change in an intermediate filament of the newt, Notophthalmus viridescens, during limb regeneration.Cell and tissue research · 1990Article
- Contrary effect of lactic acid on expression of neuron-specific enolase and glial fibrillary acidic protein in human glioma cells.Acta neuropathologica · 1990Article
- Assembly and exchange of intermediate filament proteins of neurons: neurofilaments are dynamic structures.The Journal of cell biology · 1989Article
- Expression of simple epithelial type cytokeratins in stratified epithelia as detected by immunolocalization and hybridization in situ.The Journal of cell biology · 1988Article
- Molecular characterization and expression of the stratification-related cytokeratins 4 and 15.The Journal of cell biology · 1988Article
- Sequential changes of extracellular matrix and proliferation of Ito cells with enhanced expression of desmin and actin in focal hepatic injury.The American journal of pathology · 1986Article
- Intermediate-filament expression in thyroid gland carcinomas.Virchows Archiv. A, Pathological anatomy and histopathology · 1986Article
- Differential control of cytokeratins and vimentin synthesis by cell-cell contact and cell spreading in cultured epithelial cells.The Journal of cell biology · 1984Article
- Localization of actin and myosin for the study of ameboid movement in Dictyostelium using improved immunofluorescence.The Journal of cell biology · 1984Article
- Identification of cells from fetal bladder epithelium in human amniotic fluid.Human genetics · 1984Article
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Authors and funding
4 authors.
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Abstract
We describe reversible changes of intermediate filaments of fibroblastic cells associated with changes in the functional state of the cells. The changes are revealed by comparing the immunofluorescence patterns given by a monoclonal antibody and a polyclonal serum, both recognizing vimentin. The state of the filaments depends on culture density; this effect cannot be attributed to the nutritional state of the cells, their growth rate, or substances released into the medium. It seems to depend mainly on the aggregation of filaments during strong cell movements. The possible significance of these findings for the functional role of intermediate filaments is discussed.
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